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This study aimed to assess the impact of SARS-CoV-2 therapies on the risk of venous thromboembolism (VTE) and other cardiovascular events. A retrospective, multicenter, observational study included hospitalized patients in Spain due to acute SARS-CoV-2 infection from March 2020 to March 2022. A tota...

Objective

To develop and validate a prediction model of mortality in patients with COVID-19 attending hospital emergency rooms.

Design

Multivariable prognostic prediction model.

Setting

127 Spanish hospitals.

Participants

Derivation (DC) and external validation (VC) coho...

Background

Ventilation management may differ between COVID-19 ARDS (COVID-ARDS) patients and patients with pre-COVID ARDS (CLASSIC-ARDS); it is uncertain whether associations of ventilation management with outcomes for CLASSIC-ARDS also exist in COVID-ARDS.

Methods

Individual patient ...

Background

Acute diverticulitis is a common condition that can be a surgical emergency. Its prevalence is increasing worldwide, however optimal management remains unclear. This study aimed to determine current practice and short-term outcomes globally.

Methods

A prospective, internati...

Introduction

Restoration of surgical capacity is essential to post-COVID-19 recovery. This study explored the use and safety of anaesthesia options for inguinal hernia surgery, a common tracer condition, to describe current global practice and highlight opportunities to build the capacity of...

Background

Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.

Methods

The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death ...
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