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ProteomicsGenetic manipulation of Hmr leads to altered protein-protein interactions network
In this study we use Affinity Purification coupled with Mass Spectrometry (AP-MS) to test the effect of HMR overexpression (Hmr.over) or mutation (Hmr.dC and Hmr.2) on the interactome of HMR and in relation to the Speciation Core Complex (SCC). All affinity purifications were performed with a FLAG a...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-08-11 | PXD023193 | Pride
: chromatin  speciation  nucleolus  centromere  heterochromatin  chromocenter  drosophila  development  hybrids  hmr  bess  hmrdc  hmr2 
ProteomicsThe protein-protein interaction network of the Drosophila Speciation Core Complex
In this study we described the protein-protein interaction network of the Drosophila Speciation Core Complex by analysing the interactome of its subunit: HMR, LHR, NLP, BOH1 (CG33213), BOH2 (CG4788) and HP1a. For this purpose we performed Affinity Purification coupled with Mass Spectrometry (AP-MS) ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-08-11 | PXD023188 | Pride
Chromatin  speciation  nucleolus  centromere  heterochromatin  chromocenter  drosophila  development  hybrids  nlp  nph  nucleoplasmin  nucleophosmin  hp1a  hmr  lhr  boh1  boh2 
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