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TranscriptomicsInsights into microbial modulation of host peripheral lipid and glucose metabolism using mouse gut organoids
The gastrointestinal microbiota is involved in the development of various diseases, such as obesity and diabetes, by affecting nutrient acquisition, energy balance, and metabolic signaling of the host. However, the underlying mechanisms of these host-microbiota interactions remain unclear. The aim o...
ORGANISM(S): Mus musculus 
2014-07-23 | E-GEOD-59644 | biostudies-arrayexpress
GenomicsIntegrative genomic analysis of CREB defines a critical role for transcription factor networks in mediating the fed/fasted switch in liver [ChIP-seq]
Metabolic homeostasis in mammals critically depends on the regulation of fasting-induced genes by CREB in the liver. Previous genome-wide analysis has shown that only a small percentage of CREB target genes are induced in response to fasting-associated signaling pathways. The precise molecular mecha...
ORGANISM(S): Mus musculus 
2013-05-01 | E-GEOD-45674 | biostudies-arrayexpress
TranscriptomicsIntegrative genomic analysis of CREB defines a critical role for transcription factor networks in mediating the fed/fasted switch in liver [array]
Metabolic homeostasis in mammals critically depends on the regulation of fasting-induced genes by CREB in the liver. Previous genome-wide analysis has shown that only a small percentage of CREB target genes are induced in response to fasting-associated signaling pathways. The precise molecular mecha...
ORGANISM(S): Mus musculus 
2013-05-01 | E-GEOD-45731 | biostudies-arrayexpress
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