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ProteomicsIdentification of cGAS post-translational modifications
DNA derived from the genetic material of pathogens or from cellular DNA damage provides a molecular pattern that can be sensed by pattern-recognition receptors of the mammalian innate immune system. In recent years, the cyclic GMP-AMP synthase (cGAS) protein has been characterized as a primary cytos...
ORGANISM(S): Homo Sapiens 
2020-05-08 | PXD017133 | panorama
ProteomicsPRM quantification of MCS proteins and viral proteins in HCMV virus microenvironment
The control of host processes which influence cell-cell communication is central to determining the outcome of a virus infection in tissue. Despite this, it remains unclear how cells either in close or distant proximity to an infected cell differentially respond to the primary infection. We establis...
ORGANISM(S): Homo Sapiens Human Betaherpesvirus 5 
PXD038466 | panorama
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