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TranscriptomicsRNA-seq of wild-type, Pbx1/Pbx2 double-knockout and pMsgn1-mut EpiSCs differentiated in vitro to pre-somitic mesoderm in the first 24 hours of differentiation.
In vertebrates, body axis elongation is fuelled by bipotent neuromesodermal progenitors (NMPs), which support the development of both spinal cord and paraxial mesoderm (PM). HOX transcription factors have been historically implicated in axial elongation, with their sequential activation playing a fu...
ORGANISM(S): Mus musculus 
2021-07-21 | E-MTAB-9773 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for Chronic Lymphocytic Leukemia_diagnostic sample_patient samples
High-resolution genomic microarrays provides simultaneous detection of copy-number aberrations such as the known recurrent aberrations in Chronic Lymphocytic Leukemia_diagnostic sample_patient (del(11q), del(13q), del(17p) and trisomy 12), and copy-number neutral loss of heterozygosity. We screened...
ORGANISM(S): Homo sapiens 
2011-04-28 | E-GEOD-28030 | biostudies-arrayexpress
UnknownSpatial aspects of oncogenic signalling determine the response to combination therapy in slice explants from Kras-driven lung tumours.
Not available
S-EPMC5947161 | biostudies-literature
TranscriptomicsRNA-seq of whole tissue of 3 days post fertilization atp6v1e1b-deficient zebrafish larvae and wild-type controls
Cutis laxa (CL) syndromes are a heterogenous group of connective tissue disorders that share a loose, redundant skin as a common clinical feature. The systemic features vary among the different subtypes. CL is caused by mutations in genes encoding for components of the extracellular matrix (FBLN4, F...
ORGANISM(S): Danio rerio 
2021-01-29 | E-MTAB-8824 | biostudies-arrayexpress
TranscriptomicsGenomic architecture characterizes tumor progression paths and fate in breast cancer patients
Distinct molecular subtypes of breast carcinomas have been identified, but translation into clinical use has been limited. We have developed two platform independent algorithms to explore genomic architectural distortion using array comparative genomic hybridization (aCGH) data to measure 1) whole a...
ORGANISM(S): Homo sapiens 
2009-12-15 | E-GEOD-19425 | biostudies-arrayexpress
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