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MetabolomicsFecal Microbiota Transplantation Restores Gut Homeostasis and Enhances ER-Phagy to Mitigate Radiation-Induced Lung Injury

Radiation-induced lung injury (RILI) is a severe side effect of radiation therapy, characterized by lung tissue damage, inflammation, and organ dysfunction. Although fecal microbiota transplantation (FMT) has shown potential in alleviating radiation-induced damage, its underlying mechanisms ...

2026-01-05 | MTBLS12699 | MetaboLights
MetabolomicsBerberine alleviates radiation-induced lung injury through promoting microbiota-derived inosine via gut-lung axis

Radiation-induced lung injury (RILI) is a major complication of thoracic radiotherapy. A previous study has indicated an association between berberine (BBR) and reduced incidence of RILI. However, the underlying mechanisms remain unknown. Here we validated the radioprotective role of BBR in mouse...

2025-05-14 | MTBLS12391 | MetaboLights
MetabolomicsMetabolomics of lung injury after allogeneic hematopoietic cell transplantation - Lung NMR HSQC
Not available
ORGANISM(S): Mus musculus 
ST001460 | MetabolomicsWorkbench
MetabolomicsMetabolomics of lung injury after allogeneic hematopoietic cell transplantation - Lung DI-FTMS
Not available
ORGANISM(S): Mus musculus 
ST001469 | MetabolomicsWorkbench
MetabolomicsSuccinate accumulation drives ischaemia-reperfusion injury during organ transplantation
During heart transplantation, storage in cold preservation solution is thought to protect the organ by slowing metabolism; by providing osmotic support; and by minimising ischaemia-reperfusion (IR) injury upon transplantation into the recipient. Despite its widespread use, our understanding of the m...
2019-09-20 | MTBLS1085 | MetaboLights
MetabolomicsMetabolomics of lung injury after allogeneic hematopoietic cell transplantation - Lung ICMS
Not available
ORGANISM(S): Mus musculus 
ST001470 | MetabolomicsWorkbench
MetabolomicsMetabolomics of lung injury after allogeneic hematopoietic cell transplantation - Lung NMR 1D
Not available
ORGANISM(S): Mus musculus 
ST001459 | MetabolomicsWorkbench
MetabolomicsMetabolomics of lung injury after allogeneic hematopoietic cell transplantation - Liver ICMS
Not available
ORGANISM(S): Mus musculus 
ST001453 | MetabolomicsWorkbench
MetabolomicsMetabolomics of lung injury after allogeneic hematopoietic cell transplantation - Spleen ICMS
Not available
ORGANISM(S): Mus musculus 
ST001474 | MetabolomicsWorkbench
MetabolomicsMetabolomics of lung injury after allogeneic hematopoietic cell transplantation - Colon ICMS
Not available
ORGANISM(S): Mus musculus 
ST001447 | MetabolomicsWorkbench
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