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ProteomicsGlucosidase Alpha Neutral C Promotes Influenza Virus Replication by Inhibiting Proteosome-Dependent Degradation of Hemagglutinin
The H7N9 influenza virus poses a significant threat to human health, and the mechanism by which it infects humans remains incompletely understood. Our investigation has unveiled significant insights into the role of glucosidase alpha, neutral C (ganc) gene in human H7N9 infections. Through whole gen...
ORGANISM(S): Homo Sapiens 
2025-03-10 | PXD061732 |
TranscriptomicsCRL5-WSB2 Inactivation Drives BIM/NOXA-Mediated Neuronal Apoptosis in Luo-Agrawal Syndrome
Biallelic mutations in WSB2 have recently been linked to Luo-Agrawal syndrome, a newly recognized neurodevelopmental disorder characterized by severe microcephaly and brain hypoplasia; however, the precise molecular mechanisms driving this disease remain elusive. Here, we identify the multi-subunit ...
ORGANISM(S): Mus musculus 
2026-09-10 | GSE345497 | GEO
TranscriptomicsCRL5-WSB2 Inactivation Drives BIM/NOXA-Mediated Neuronal Apoptosis in Luo-Agrawal Syndrome [hCOs]
Biallelic mutations in WSB2 have recently been linked to Luo-Agrawal syndrome, a newly recognized neurodevelopmental disorder characterized by severe microcephaly and brain hypoplasia; however, the precise molecular mechanisms driving this disease remain elusive. Here, we identify the multi-subunit ...
ORGANISM(S): Homo sapiens 
2026-09-10 | GSE345590 | GEO
ModelsLuo1991_VentricularCardiacAction
This a model from the article: A model of the ventricular cardiac action potential. Depolarization, repolarization, and their interaction. Luo CH, Rudy Y. Circ Res. 1991 Jun;68(6):1501-26. 1709839 , Abstract: ...
2005-01-01 | MODEL0479527919 | BioModels
ModelsLuo1994_CardiacVentricularActionPotential
This a model from the article: A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes. Luo CH, Rudy Y. Circ Res 1994 Jun;74(6):1071-96 7514509 , Abstract: ...
2005-01-01 | MODEL0912160003 | BioModels
TranscriptomicsPQM-1 and Cobalt Chloride dependent gene expression changes in C. elegans
Worms were exposed to 5 mM CoCl2 at the early day 1 of adulthood stage for 6 hr and 20 hr. Untreated worms were used as controls. Worms were collected, RNA isolated and hybridized on 4x44K C. elegans arrays (Agilent) at 60C overnight, as previously described 1). Three biological replicates were used...
ORGANISM(S): Caenorhabditis elegans 
2020-07-08 | GSE139562 | GEO
ProteomicsTMT labeled Comparative Proteomic Analysis Reveals Active Immune Response during Clostridium perfringens type C Infected Piglet Diarrhea
We performed a TMT labeling-based quantitative spleen proteomic analysis of the control group (SC), tolerance group (SR) and susceptible group (SS) to identify the differentially expressed proteins (DEPs), and screened potential molecular markers of piglet spleen tissues in response to C. perfringen...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-05-20 | PXD030745 | Pride
Tmt labeling  proteome  clostridium perfringens type c  piglet diarrhea  immune response  spleen 
GenomicsPQM-1 and Cobalt Chloride dependent gene expression changes in C. elegans
PQM-1 and Cobalt Chloride dependent gene expression changes in C. elegans
PRJNA580256 | ENA
UnknownEarly predictive efficacy of core antigen on antiviral outcomes in genotype 1 hepatitis C virus infected patients.
Not available
S-EPMC9427537 | biostudies-literature
TranscriptomicsDevelopmental timecourse of C. elegans small RNAs with 5p monophosphates
These datasets profile the expression of small RNAs with 5p monophosphates and 3p hydroxyls (including miRNAs, 21U-RNAs) across C. elegans development and in dauer, glp-4 mutant, and mixed-stage wt worms. These datasets were prepared in the David P. Bartel laboratory using T4 RNA ligase Rnl2(1-249)....
ORGANISM(S): Caenorhabditis elegans 
2008-06-15 | E-GEOD-11734 | biostudies-arrayexpress
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