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Background & Aims: Spirulina, a microalgae renowned for its nutrient density, shows promise in modulating glucose and lipid metabolism. However, its efficacy and underlying mechanisms against metabolic dysfunction-associated steatotic liver disease (MASLD) remain unclear. We hypothesized that spirul...
2026-06-30 | MTBLS14901 | MetaboLights
Background & Aims: Spirulina, a microalgae renowned for its nutrient density, shows promise in modulating glucose and lipid metabolism. However, its efficacy and underlying mechanisms against metabolic dysfunction-associated steatotic liver disease (MASLD) remain unclear. We hypothesized that spirul...
2026-06-30 | MTBLS14903 | MetaboLights
Left displaced abomasum (LDA) leads to substantial changes in the metabolism of dairy cows. Surgical correction of LDA can rapidly improve the health of cows; however, changes in metabolism following surgery are rarely described. To investigate the changes of plasma metabolome in cows with LDA befor...
2022-08-17 | MTBLS4126 | MetaboLights
Bacillus subtilis encodes seven extracytoplasmic function (ECF) sigma factors. Three (sigma M, sigma W and simga X) mediate responses to cell envelope active antibiotics. The functions of sigma Y, sigma Z, sigma V, and YlaC remain largely unknown, and strong inducers of these sigma factors and their...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
We used Global Run-on and Sequencing (GRO-seq) to measure the rate of transcription elongation by RNA polymerase II (Pol II) following gene activation. We observed that Pol II elongation rates can vary as much as 4-fold at different genomic loci and in response to two distinct cellular signaling pa...
ORGANISM(S): Homo sapiens 
The mutation in the budding yeast gene PCNA, pol30-8, as well as deletion of DOT1 (dot1Δ), encoding the only histone H3 K79 methyltransferase in budding yeast, have been implicated in telomeric silencing. To further analyze these mutants, we used microarrays to study whether either pol30-8, dot1Δ or...
ORGANISM(S): Saccharomyces cerevisiae 

Left displaced abomasum (LDA) in postpartum dairy cows contributes to significant economic losses. LDA is characterized by excessive lipolysis and insulin resistance. Although gut dysbiosis is implicated, little is known about the role of the gut microbiota in the abnormal metabolic processes of ...

2022-08-17 | MTBLS2441 | MetaboLights
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