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no omics definedTranscription profiling of human cell lines and tissues - Luscombe re-analysis of GNF/Novartis data
The expression data utilized in this analysis derives from the raw data published by Su et al. 2004 (also known as GNF/Novartis dataset or E-AFMX-5 in ArrayExpress, GSE1133 and GDS596 in GEO). The data contains 79 different human tissues and cell types with 2 replicates per tissue/cell type. The dat...
ORGANISM(S): Homo sapiens 
2008-02-23 | E-TABM-145 | biostudies-arrayexpress
UnknownDiscovery and Optimization of Potent and CNS Penetrant M5-Preferring Positive Allosteric Modulators Derived from a Novel, Chiral N-(Indanyl)piperidine Amide Scaffold.
Not available
S-EPMC6104635 | biostudies-literature
TranscriptomicsIndividual-nucleotide resolution CLIP and high-throughput sequencing to map hnRNP L-RNA interactions in HeLa cells
Individual-nucleotide resolution UV-crosslinking and immunoprecipitation (iCLIP) combined with high-throughput sequencing was used to generate a transcriptome-wide binding map of hnRNP L. Supplementary file GSE37560_hnRNPL_crosslink_site.bed includes filtered crosslink sites of hnRNPL: combining da...
ORGANISM(S): Homo sapiens 
2014-02-13 | E-GEOD-37560 | biostudies-arrayexpress
TranscriptomicsChiP-chip profiling of Drosophila melanogaster cell lines to identify targets for nuclear pore proteins Nup153 and Megator.
ChIP-chip experiment for nuclear pore proteins Nup153 and Mtor in Drosophila S2 and Kc cells. This experiment is related to E-MEXP-2523.
ORGANISM(S): Drosophila melanogaster 
2010-02-12 | E-MEXP-2525 | biostudies-arrayexpress
TranscriptomicsCLIP-Seq of human HeLa cells to enable precise mapping of protein-RNA interactions in intact cells
UV-crosslinking and immunoprecipitation (CLIP) combined with high-throughput sequencing was previously used to generate transcriptome-wide binding maps of several RNA-binding proteins9-12. However, since identification of binding sites relied on the analysis of overlapping sequence clusters, distanc...
ORGANISM(S): Homo sapiens 
2010-10-01 | E-MTAB-341 | biostudies-arrayexpress
TranscriptomicsPervasive TTP binding but selective target mRNA destabilization in the macrophage transcriptome [PAR-iCLIP]
Precise control of mRNA decay is fundamental for robust yet not exaggerated inflammatory responses to pathogens. Parameters determining the specificity and extent of mRNA degradation within the entire inflammation-associated transcriptome remain incompletely understood. Using transcriptome-wide high...
ORGANISM(S): Mus musculus 
2016-05-17 | E-GEOD-63466 | biostudies-arrayexpress
UnknownMolecular fossils in the human genome: identification and analysis of the pseudogenes in chromosomes 21 and 22.
Not available
S-EPMC155275 | biostudies-literature
TranscriptomicsA gene regulatory network for neural induction
During early vertebrate development, signals from a special region of the embryo, the organizer, can re-direct the fate of non-neural ectoderm cells to form a complete, patterned nervous system. The process has generally been imagined as the result of a single signaling event, causing a simple switc...
ORGANISM(S): Gallus gallus 
2023-03-14 | E-MTAB-10408 | biostudies-arrayexpress
TranscriptomicshnRNP L-RNA in HeLa
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-02-13 | E-GEOD-37562 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation to determine MSL1, MSL3, MOF and H4K16Ac binding in Drosophila SL2 and Kc cells reveals MOF as a key regulator of dosage compensation and gene expression in Drosophila
Genome-wide binding profiles of MSL1, MSL3, MOF and H4K16Ac in Drosophila SL2 and Kc cells.
ORGANISM(S): Drosophila melanogaster 
2008-06-12 | E-MEXP-1508 | biostudies-arrayexpress
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