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TranscriptomicsEscherichia coli K-12: luxS mutant LW12 vs. wild type W3110
Transcripitonal profiling of Escherichia coli K-12 comparing luxS mutant LW12 with wild type W3110 One-condition experiment, luxS mutant LW12 vs. wild type W3110
ORGANISM(S): Escherichia coli 
2010-11-11 | E-GEOD-20606 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E.coli luxS mutants vs. W3110 wild type
The bacterial quorum-sensing autoinducer 2 (AI-2) has received intense interest because the gene for its synthase, luxS, is common among a large number of bacterial species. We have identified luxS-controlled genes in Escherichia coli under two different growth conditions using DNA microarrays. Twen...
ORGANISM(S): Escherichia coli 
2008-06-16 | E-GEOD-9587 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli K12 luxS-dependent gene regulation
The bacterial quorum-sensing autoinducer 2 (AI-2) has received intense interest because the gene for its synthase, luxS, is common among a large number of bacterial species. We have identified luxS-controlled genes in Escherichia coli under two different growth conditions using DNA microarrays. Twen...
ORGANISM(S): Escherichia coli 
2008-06-16 | E-GEOD-9582 | biostudies-arrayexpress
TranscriptomicsLuxS signaling system and regulation of pneumococcal genes
We were interested in determining if the LuxS signaling system contributed to the regulation of pneumococcal genes. To accomplish this, we compared the in vitro transcriptional profiles over time of S. pneumoniae D39, a serotype 2 strain of pneumococcus, with that of an isogenic deletion mutant, (d...
ORGANISM(S): Streptococcus pneumoniae 
2005-08-03 | E-GEOD-3046 | biostudies-arrayexpress
TranscriptomicsWild type E.coli SE15 vs. LuxS mutant E.coli SE15
Transcriptional profiling of E.coli SE15 comparing wild type E.coli SE15 with Autoindecur 2 synthesis gene LuxS mutnat E.coli SE15. E.coli SE15 is isolated from indwelling catheter of urinary tract infected patient. Examine change of quorum sensing related gene by deleting autoinducer 2 synthesis g...
ORGANISM(S): Escherichia coli SE15 
2013-08-02 | E-GEOD-49474 | biostudies-arrayexpress
TranscriptomicsLuxS/AI-2 quorum sensing microarray comparison in Yersinia pestis at 30°C
The AI-2 quorum-sensing system has been linked to diverse phenotypes and regulatory changes in pathogenic bacteria. In strain CO92, the AI-2 signal is produced in a luxS-dependent manner, reaching maximal levels of 2.5 μM in late logarithmic growth, and both wild type and pigmentation mutant strain...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30108 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of luxS-null strain in Yersinia pestis CO92 at 37M-BM-0C
Yersinia pestis, the etiological agent of plague, is able to sense cell density by quorum sensing. The function of quorum sensing in Y. pestis is not clear. Here, the process of autoinducer 2 (AI-2) quorum sensing was investigated by comparing transcript profiles when luxS gene was knocked out. The ...
ORGANISM(S): Yersinia pestis 
2013-09-05 | E-GEOD-22849 | biostudies-arrayexpress
TranscriptomicsAI-2-dependent gene regulation in Staphylococcus epidermidis
Autoinducer 2 (AI-2), a widespread by-product of the LuxS-catalyzed S-ribosylhomocysteine cleavage reaction in the activated methyl cycle, has been suggested to serve as an intra- and interspecies signaling molecule, but in many bacteria AI-2 control of gene expression is not completely understood. ...
ORGANISM(S): Staphylococcus epidermidis 
2008-10-10 | E-GEOD-9427 | biostudies-arrayexpress
TranscriptomicsEscherichia coli K-12: 0%, 10% and 30% hydrogen peroxide (H2O2) treatments, in wild type and luxS mutants
Transcripitonal profiling of Escherichia coli K-12 W3110 comparing wild type and luxS mutants without or with 10%, 30% H2O2 treatments, two biological replicates for each condition two-variables experiments: samples without or with treatment of 10% or 30% H2O2 for 30min; wild type and luxS mutants
ORGANISM(S): Escherichia coli 
2015-05-19 | E-GEOD-38186 | biostudies-arrayexpress
TranscriptomicsRNA-sequencing of WT and luxS mutant Clostridioides difficile during planktonic culture
RNA-sequencing comparing C. difficile WT and luxS mutant after 8 hours growth in planktonic conditions. Sequencing was performed in triplicate, from biological replicates grown in BHI medium.
ORGANISM(S): Clostridioides difficile 
2018-12-16 | E-MTAB-7486 | biostudies-arrayexpress
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