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TranscriptomicsThe tremendous effect of the rational ribosomal engineering on the transcriptome in Streptomyces albus nalyzed by RNA-seq of coding RNA.
To elucidate the effect of the rational ribosomal engineering on the changes in the expression of the endogenious biosynthetic gene clusters the transcriptome analysis was performed. The Streptomyces albus strains carrying mutations in rpsL gene (encode for ribosomal protein S12) and the deletion of...
ORGANISM(S): Streptomyces albus J1074 
2019-05-01 | E-MTAB-7715 | biostudies-arrayexpress
TranscriptomicsGeneration of new compounds through unbalanced transcription of landomycin A cluster
On the example of the biosynthetically exhausted landomycin A cluster we demonstrate unbalancing of gene transcription as an efficient method for the generation of new compounds. Decoupled from the native regulators LanI and LanK, all landomycin A structural genes were set under the control of a sin...
ORGANISM(S): Streptomyces albus 
2016-07-01 | E-GEOD-83137 | biostudies-arrayexpress
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