Sort   by:  
 Page size 
MetabolomicsMethionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
TranscriptomicsPbx1-d Induces T cell Activation and a Decreased Apoptosis in Response to Retinoic Acids (RA)
The hypothesis was tested that the Pbx1-d isoform was responsible for the Sle1a.1 phenotypes in CD4+ T cells. Jurkat T cells were transfected with a lentiviral construct expressing Pbx1-d-GFP or control RFP. Pbx1-d over-expression reduced the percentage of late apoptotic cells in response to anti-C...
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-22799 | biostudies-arrayexpress
UnknownAssociations of inflammation related prenatal adversities with neurodevelopment of offspring in one year: a longitudinal prospective birth cohort study.
Not available
S-EPMC11445952 | biostudies-literature
TranscriptomicsThe Lin28b-let-7-Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells
Mouse haematopoietic stem cells (HSCs) undergo a post-natal transition in several properties, including a marked reduction in their self-renewal activity. We now show that the developmentally timed change in this key function of HSCs is associated with their decreased expression of Lin28b and an acc...
ORGANISM(S): Mus musculus 
2013-06-27 | E-GEOD-41758 | biostudies-arrayexpress
UnknownLeft atrial reservoir strain combined with E/E' as a better single measure to predict elevated LV filling pressures in patients with coronary artery disease.
Not available
S-EPMC7183713 | biostudies-literature
Proteomicsthe analysis of sus scrofa serum LC-MS/MS after african swine fever virus infection
African swine fever (ASF) is the most dangerous disease of pigs and causes enormous economic losses in the global pig industry. However, the mechanism of ASF virus (ASFV) infection is unclear. Hence, we wanted to understand the host response mechanism upon ASFV infection. We analyzed the differentia...
ORGANISM(S): Viruses Sus scrofa domesticus (domestic pig) 
2022-10-12 | PXD035545 | Pride
Sus scrofa serum lc-ms/ms 
TranscriptomicsMutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy
Left ventricular noncompaction (LVNC) Causes prominent ventricular trabeculations and reduces cardiac systolic function. The clinical presentation of LVNC ranges from asymptomatic to heart failure. We show that germline mutations in human MIB1 (mindbomb homolog 1), which encodes an E3 ubiquitin liga...
ORGANISM(S): Mus musculus 
2015-08-10 | E-GEOD-71912 | biostudies-arrayexpress
UnknownA novel method to prepare L-arabinose from xylose mother liquor by yeast-mediated biopurification.
Not available
S-EPMC3125199 | biostudies-literature
UnknownRapid Identification of Benign Gallbladder Diseases Using Serum Surface-Enhanced Raman Spectroscopy Combined with Multivariate Statistical Analysis.
Not available
S-EPMC9955438 | biostudies-literature
UnknownIntracoronary administration of cardiac stem cells in mice: a new, improved technique for cell therapy in murine models.
Not available
S-EPMC3640450 | biostudies-literature
Sort   by:  
 Page size