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TranscriptomicsSingle-cell 5' Gene Expression and V(D)J Amplification (10X Genomics) of splenic CD4+ T cells from Plasmodium chabaudi infected mice
To associate gene expression profiles with specific features of the splenic CD4+ T-cell repertoire generated during a blood stage P. chabaudi infection, we obtained both transcriptomic and T-cell receptor data from 2 infected mice at 7 days following infection.
ORGANISM(S): Mus musculus 
2020-11-13 | E-MTAB-9691 | biostudies-arrayexpress
UnknownAmelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Not available
S-EPMC10922706 | biostudies-literature
UnknownTargeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation.
Not available
S-EPMC5919821 | biostudies-literature
TranscriptomicsGene expression analysis of rectal mucosa in chronic irritable bowel syndrome (IBS) compared to healthy volunteers (HV)
An investigation of gene expression changes in rectal biopsies from donors with IBS compared to controls to begin to understand this complex syndrome. To further investigate differences between IBS groups (constipation and diarrhoea predominant) (part1) and how IBS relates to bacterial infection (pa...
ORGANISM(S): Homo sapiens 
2012-07-12 | E-GEOD-36701 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Baseline gene expression in circulating peripheral blood mononuclear cells isolated from 18 apparently healthy volunteers (10 females and 8 males)
Baseline gene expression in circulating peripheral blood mononuclear cells isolated from 18 apparently healthy volunteers (10 females and 8 males). The volunteers fasted overnight for 10 hours prior to collection of blood samples (but they were allowed water). 5 blood samples were collected from eac...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-TABM-7 | biostudies-arrayexpress
TranscriptomicsThe Wnt/β-catenin-signaling pathway is modulated by androgen ablation therapy for advanced clinical prostate cancer and contributes to androgen independent cell growth
Androgen ablation therapy (AAT) is standard treatment for locally-advanced/metastatic prostate cancer (PCa). Many patients develop castration-resistance (CRPCa) after ~2-3 years, with a poor prognosis. The molecular mechanisms underlying CRPCa progression are unclear. mRNA-Seq was performed on tu...
ORGANISM(S): Homo sapiens 
2013-10-07 | E-GEOD-48403 | biostudies-arrayexpress
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