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MetabolomicsER stress inhibits liver fatty acid oxidation while unmitigated stress leads to anorexia-induced lipolysis and both liver and kidney steatosis
The unfolded protein response (UPR), induced by endoplasmic reticulum (ER) stress, regulates the expression of factors that restore protein folding homeostasis. However, in the liver and kidney, ER stress also leads to lipid accumulation, accompanied at least in the liver by transcriptional suppress...
2017-06-23 | MTBLS472 | MetaboLights
TranscriptomicsTranscriptomic analysis of the stress response to weaning at housing in bovine leukocytes using RNA-seq technology
Background: Weaning of beef calves is a necessary husbandry practice and involves separating the calf from its mother, resulting in numerous stressful events including dietary change, social reorganisation and the cessation of the maternal-offspring bond and is often accompanied by housing. While mu...
ORGANISM(S): Bos taurus 
2012-06-25 | E-GEOD-37447 | biostudies-arrayexpress
UnknownChanges in mumps virus gene sequence associated with variability in neurovirulent phenotype.
Not available
S-EPMC229304 | biostudies-literature
UnknownGlobal gene expression and systems biology analysis of bovine monocyte-derived macrophages in response to in vitro challenge with Mycobacterium bovis.
Not available
S-EPMC3284544 | biostudies-literature
ProteomicsStructure of an essential inner membrane protein-LPS complex identifies a novel anti-microbial peptide
Lipopolysaccharide (LPS) resides in the outer membrane (OM) of Gram-negative bacteria where it is responsible for barrier function and immune modulation. LPS is the target of polymyxins, last-resort antibiotics whose clinical use is threatened by increasing resistance. Steps in LPS biogenesis are ...
ORGANISM(S): Escherichia Coli K-12 (ncbitaxon:83333) 
2019-05-08 | MSV000083754 | MassIVE
UnknownPegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration.
Not available
S-EPMC3532820 | biostudies-literature
UnknownAutologous Ex Vivo Lentiviral Gene Therapy for Adenosine Deaminase Deficiency.
Not available
S-EPMC8240285 | biostudies-literature
Unknown"We are looking at the future right now": community acceptability of a home-based viral load test device in the context of HIV cure-related research with analytical treatment interruptions in the United States.
Not available
S-EPMC9519804 | biostudies-literature
UnknownThe impact of COVID-19 on alternative and local food systems and the potential for the sustainability transition: Insights from 13 countries.
Not available
S-EPMC10225305 | biostudies-literature
UnknownParticipant experiences using novel home-based blood collection device for viral load testing in HIV cure trials with analytical treatment interruptions
Not available
S-EPMC9403870 | biostudies-literature
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