Background The role of dietary interventions, particularly lysine-restricted diets(LRD), in mitigating obesity-associated anxiety-like behaviors remains poorly understood, with limited insight into gut microbiota-metabolite-brain axis mechanisms.

Results LRD significantly improved anxiety b...

The influence of amino acid restriction on obesity may be related to the gut microbiome, but the role and mechanism of lysine restriction (LR) on pediatric obesity is largely undefined. Here, we found plasma lysine levels were significantly higher in obese patients than healthy controls of childr...

Mycobacterium tuberculosis (Mtb) survives host defences by adapting to host conditions, including acid stress, during infection. A critical survival strategy involves pH homeostasis, mediated by complex signalling systems that regulate metabolic reprogramming and stress responses. While ...