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MetabolomicsMetabolic effect of the loss of mitochondrial-specific aspartyl-tRNA synthetase Das2 on mouse intestinal epithelial cells
Not available
ORGANISM(S): Mus musculus 
ST002184 | MetabolomicsWorkbench
MetabolomicsMultiple modes of interfering with the activity of Plasmodium falciparum cytoplasmic isoleucyl-tRNA synthetase illustrate the enzyme is a promising antimalarial target.
Not available
ORGANISM(S): Plasmodium falciparum 
ST002078 | MetabolomicsWorkbench
ProteomicsYeast glutamine tRNA synthetase doxycycline shut-off
During protein synthesis, charged tRNAs deliver amino acids to translating ribosomes, and are then re-charged by tRNA synthetases (aaRS). In humans, mutant aaRS cause a diversity of neurological disorders, but their molecular aetiologies are incompletely characterised. To understand system responses...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-02-12 | PXD017140 | Pride
Saccharomyces cerevisiae Silac Translation Trna synthetase depletion 
ProteomicsIsoleucyl-tRNA synthetase interactome analysis
Aminoacyl-tRNA synthetases (aaRSs) catalyze the ligation of each amino acid to the 3’ hydroxyl group of the cognate tRNA and thereby establish the genetic code for protein synthesis. AaRSs form a complicated network through assembly into a multi-synthetase complex (MSC), which is comprised of nine a...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD031261 | Pride
Trna synthetase Interactome Structure Lc-ms/ms 
UnknownA bacterial ortholog of class II lysyl-tRNA synthetase activates lysine.
Not available
S-EPMC2900529 | biostudies-literature
ProteomicsMETTL21C methylates Alanine tRNA synthetase at lysine 943 in muscle tissue
Protein lysine methylation is a common post-translational modification (PTM) detected throughout the human proteome that plays important roles in diverse biological processes. In the human genome, there are greater than one hundred known and candidate protein lysine methyltransferases (PKMTs), many ...
ORGANISM(S): Homo sapiens (Human) 
2020-07-02 | PXD019886 | Pride
Human Methylation Aars1 Lc-ms/ms 
UnknownLysine Acetylation Regulates Alanyl-tRNA Synthetase Activity in Escherichia coli.
Not available
S-EPMC6209979 | biostudies-literature
UnknownThe catalytic flexibility of tRNAIle-lysidine synthetase can generate alternative tRNA substrates for isoleucyl-tRNA synthetase.
Not available
S-EPMC2665086 | biostudies-literature
UnknownBiochemical Characterization of the Lysine Acetylation of Tyrosyl-tRNA Synthetase in Escherichia coli.
Not available
S-EPMC5629106 | biostudies-literature
UnknownPyrrolysyl-tRNA Synthetase with a Unique Architecture Enhances the Availability of Lysine Derivatives in Synthetic Genetic Codes.
Not available
S-EPMC6222415 | biostudies-literature
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