M1 - OmicsDI

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Unknown (12863)
Transcriptomics (3059)
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Organisms

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cellular organisms (7)
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root (1)
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Organisms

Mus musculus (561)
Homo sapiens (432)
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marine metagenome (35)
Rattus norvegicus (27)
Streptococcus pyogenes M1 GAS (11)
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Drosophila melanogaster (9)
Arabidopsis thaliana (8)
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hot springs metagenome (5)
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fermentation metagenome (3)
Bos taurus (3)
Zea mays (3)
mouse gut metagenome (3)
Fructobacillus papyriferae (2)
Oceanispirochaeta sp. M1 (2)
Listeria fleischmannii subsp. coloradonensis (2)

Repository

biostudies-arrayexpress (2401)
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geo (949)
pride (231)
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Tissue

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Healthy (1)
Murine hemochromatosis (1)
IRAK-4 Q293X mutation (1)

Technology Type

Mass Spectrometry (249)
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Data-independent acquisition (15)
ESI (13)
SWATH MS (11)
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NMR spectroscopy (6)
All-ion fragmentation (5)
HDMSE (5)
EI (4)
Top-down proteomics (4)
DiaPASEF (3)
Illumina Genome Analyzer II, Illumina HiSeq 2000 (2)
Illumina HiSeq 2000 (2)
NMR spectroscopy assay (2)
Illumina MiSeq, ILLUMINA (1)
ILLUMINA, NextSeq 500 (1)
Illumina HiSeq 2000, Illumina HumanOmni5-Quad and exome sequencing, ILLUMINA (1)
Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina_Infinium_HumanMethylation450, Illumina_HumanHT-12v4 (1)
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API (1)

Instrument Platform

Illumina NovaSeq 6000 (71)
NextSeq 500 (45)
Illumina HiSeq 2500 (43)
Illumina HiSeq 2000 (33)
Illumina HiSeq 4000 (30)
NextSeq 550 (14)
Illumina NovaSeq X (13)
Illumina MiSeq (7)
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NA (3)
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Publication Date

2014 (349)
2015 (318)
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2012 (259)
2010 (234)
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2008 (144)
2020 (139)
2017 (131)
2019 (120)
2018 (104)
2009 (90)
2007 (75)
2005 (50)
2006 (23)
2004 (10)
2003 (1)

UNIPROT ID/AC

P61225 (4)
P51452 (4)
P27361 (4)
P04049 (4)
Q02750 (4)
P20963 (2)
P35225 (2)
P78552 (2)
P29597 (2)
P29350 (2)
P24394 (2)
P01270 (2)
O60674 (2)
P42229 (2)
P51692 (2)
O43526 (1)
O88944 (1)
P63231 (1)
P06820 (1)
P03437 (1)
P03508 (1)
P15659 (1)
P03427 (1)
P16511 (1)
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Q9UQC2 (1)
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P42226 (1)

ENSEMBL ID

ENSG00000168036 (1)
ENSG00000149968 (1)
ENSG00000033327 (1)
ENSG00000100985 (1)
ENSG00000102908 (1)
ENSG00000118260 (1)
ENSG00000163739 (1)
ENSG00000120659 (1)
ENSG00000170477 (1)

CHEBI ID

CHEBI:15428 (23)
CHEBI:17552 (10)
CHEBI:15422 (9)
CHEBI:15996 (3)
CHEBI:17158 (2)
CHEBI:16595 (2)
CHEBI:29108 (2)
CHEBI:18367 (2)
CHEBI:33699 (2)
CHEBI:43000 (1)
CHEBI:30111 (1)
CHEBI:38322 (1)
CHEBI:38309 (1)
CHEBI:5235 (1)
CHEBI:26667 (1)
CHEBI:5939 (1)
CHEBI:144829 (1)
CHEBI:14575 (1)
CHEBI:23008 (1)
CHEBI:17144 (1)
CHEBI:15500 (1)
CHEBI:28718 (1)
CHEBI:18041 (1)
CHEBI:16835 (1)
CHEBI:17640 (1)
CHEBI:17803 (1)
CHEBI:18090 (1)
CHEBI:17566 (1)
CHEBI:16490 (1)
CHEBI:1109 (1)

Metabolite Name

Hypoxanthine (29)
Taurine (29)
Creatine (28)
Creatinine (27)
Xanthine (26)
Adenine (25)
Inosine (25)
Xanthosine (24)
Uridine (24)
Betaine (23)
Uracil (23)
L-Glutamine (23)
Adenosine (22)
L-Tyrosine (21)
Cytosine (21)
L-Phenylalanine (21)
Riboflavin (20)
L-Tryptophan (20)
Guanosine (20)
Pantothenic acid (19)
Azelaic acid (19)
L-Histidine (19)
Deoxycholic acid (18)
Uric acid (18)
Allantoin (17)
Hippuric acid (17)
Deoxyinosine (17)
L-Proline (17)
Choline (17)
Thymine (16)

First Public Date

2024 (259)
2025 (227)
2026 (180)
2023 (161)
2022 (143)
2014 (136)
2021 (129)
2020 (107)
2019 (99)
2017 (80)
2018 (63)
2015 (41)
2016 (38)
2013 (35)
2012 (1)

Modelling Approach

Ordinary differential equation model (73)
Delayed differential equation model (2)
Logical model (2)
Mathematical model (1)

Study status

Completed (3)
Terminated (1)
Recruiting (1)

Lab affiliation

Director, Proteome Center Rostock, University of Rostock, Germany (7)
Department of Animal and Poultry Sciences and the School of Neuroscience, Virginia Tech, Blacksburg, VA, USA (5)
Parasitology Laboratory, Institute of Natural Resources and Agrobiology (IRNASA, CSIC). Cordel de Merinas, 40-52, 37008 Salamanca, Spain. (4)
Cellular Proteomics, Helmholtz Centre for Infection Research, Braunschweig, Germany (4)
Medical Research Council Mitochondrial Biology Unit, University of Cambridge. U.K. (4)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (4)
Professor of Cell Biology and NHSBT Principal Investigator,School of Biochemistry,University of Bristol (3)
Manchester Institute of Biotechnology, School of Biological Sciences, Manchester Academic Health Sciences Centre, The University of Manchester, Princess Street, Manchester, M1 7DN, UK (3)
Department of Chemistry, King’s College London, SE1 1DB, London, UK Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, M13 9PT, Manchester, UK Manchester Institute of Biotechnology, The University of Manchester, M1 7DN, Manchester, UK (2)
Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK Interdisciplinary Centre for Ancient Life, Department of Earth and Environmental Sciences, University of Manchester, Oxford Road 131, Manchester, M13 9PL, UK (2)
Université de Lille, Sciences et Technologies - INSERM U1192 - Laboratoire PRISM, France (2)
Merck & Co., Inc. (2)
Chair of Pharmacology Faculty of Medicine Jagiellonian University Medical College (2)
School of Chemistry and Biochemistry and the Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332, USA (2)
Carnegie MS facility (2)
Department for Plant Cell and Molecular Biology, Institute for Biology, Humboldt-Universität zu Berlin (2)
Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland. (2)
Army Medical University (Third Military Medical University) (2)
Department of Genetics, Department of Radiation Oncology, Cancer Genomics Netherlands, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands (1)
University of Michigan, Department of Pathology (1)
Manchester Cell-Matrix Centre, Division of Molecular and Cellular Function, FBMH, University of Manchester (1)
Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, P. R. China (1)
Interdisciplinary Research Center HALOmem, Charles Tanford Protein Center, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Straße 3a, Halle/Saale, Germany. Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Straße 3, Halle/Saale, Germany. Biozentrum, Martin Luther University Halle-Wittenberg, Weinbergweg 22, Halle/Saale, Germany. (1)
Proteomic lab., Fondazione Ri.MED (1)
Proteomic Platform of Institut de Microbiologie de la Mediterranee CNRS FR 3479 Marseille Proteomique (1)
Advanced Clinical Biosystems Research Institute, Smidt Heart Institute, Cedars-Sinai Medical Center 127 S San Vicente Blvd, Los Angeles, CA 90048, USA (1)
Molecular Evolution, Department of Cell and Molecular Biology, Science for Life Laboratory, Biomedical Centre, Uppsala University, SE-751 24 Uppsala, Sweden (1)
Tumor Biology Research Group, Department of Medical Biology, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway (1)
Dept. Cellular Molecular Pharmacology, University of San Francisco (UCSF), USA (1)
Institute of High Energy Physics, CAS (1)

Keyword

Bortezomib (1)
Methotrexate (1)
Cyclosporine (1)
Cyclophosphamide (1)
Busulfan (1)
Cyclosporins (1)
Methylprednisolone (1)
Methylprednisolone Acetate (1)
Methylprednisolone Hemisuccinate (1)
Prednisolone (1)
Prednisolone acetate (1)
Prednisolone hemisuccinate (1)
Prednisolone phosphate (1)

IsPrivate

False (79)

Model Flag

Non Kinetic (3)

Submitter Keywords

Immuno-oncology (10)
Oncology (1)

Classification

bacteria (83)
viruses (7)
protozoa (3)
fungi (2)

Modification

79.966331 (1)
15.994915 (1)
57.021464 (1)

Study type

Transcription profiling by array (1584)
RNA-seq of coding RNA (292)
ChIP-seq (125)
RNA-seq of coding RNA from single cells (44)
Unknown experiment type (36)
RNA-seq of non coding RNA (32)
Transcription profiling by RT-PCR (29)
Other (28)
MicroRNA profiling by array (28)
Comparative genomic hybridization by array (25)
Methylation profiling by array (21)
Methylation profiling by high throughput sequencing (18)
RNA-seq of total RNA (12)
Genotyping by array (11)
ATAC-seq (10)
Cell line - High-throughput sequencing (9)
Cell line - One-color microarray (8)
DNA-seq (8)
Animal - High-throughput sequencing (7)
ChIP-chip by array (6)
ChIP-chip by tiling array (5)
Human - One-color microarray (5)
Proteomic profiling by array (5)
Animal - One-color microarray (4)
Human - High-throughput sequencing (4)
Translation profiling (4)
Transcription profiling by tiling array (4)
MicroRNA profiling by high throughput sequencing (3)
RIP-seq (3)
Transcription profiling by SAGE (2)

Release Date

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2019 (775)
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2003 (17)
2002 (13)
2001 (12)
1999 (12)
1998 (9)
2000 (8)
1997 (1)

Location

United States (3)
Finland (1)
Italy (1)

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GPR109a-AMPK Axis Mediates the Attenuation of Uric Acid-Induced M1 Macrophage Polarization by β-hydroxybutyrate from Lacticaseibacillus rhamnosus M2b

Hyperuricemia (HUA) is a metabolic disorder marked by increased blood uric acid (UA) levels, closely linked to conditions such as gout. UA-induced macrophage M1 polarization fundamentally exacerbates inflammatory pathophysiology, but current HUA-specific immunoregulatory treatments are inadequat...

2026-01-26 | MTBLS13224 | MetaboLights

Whole unconditioned medium (Defined culture media, M199),Whole M1 medium,Whole M2 medium

Not available

ORGANISM(S): Homo sapiens

ST000242 | MetabolomicsWorkbench

M3-Driven Hexosamine Biosynthesis Facilitates Hepatocellular Carcinoma Progression through YBX1 O-GlcNAcylation

Phosphoglucomutase 3 (PGM3) is one of the rate-limiting enzymes in the hexosamine biosynthesis pathway (HBP) and a key regulator of HBP metabolic flux. Despite the functional role of PGM3 has been validated in various tumors, its function and molecular mechanism in hepatocellular carcinoma (HCC) rem...

2026-09-04 | MTBLS15552 | MetaboLights

2HG concentration in human IDH1m cells

Not available

ORGANISM(S): Homo sapiens

ST000824 | MetabolomicsWorkbench

Role of Hi1a in mitochondrial metabolic rewiring in M1 Macrophages

Not available

ORGANISM(S): Mus musculus

ST001282 | MetabolomicsWorkbench

Nitric Oxide (NO) effect on mitochondrial metabolic rewiring in M1 Macrophages

Not available

ORGANISM(S): Mus musculus