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MetabolomicsGut Commensal Bacteria-Derived Methionine is Required for Host Reproduction by Modulating RNA m6A Methylation of the Insulin Receptor_targeted metabolites

Gut commensal bacteria promote host reproduction by modulating metabolism and nutrition, but the molecular mechanisms by which microbes regulate reproduction remain unclear. Here, we show that gut commensal bacteria promote host reproduction by providing amino-acid methionine, which controls the ...

2025-06-22 | MTBLS12470 | MetaboLights
TranscriptomicsRNA m5C Methylation in breast cancer using MeRIP-Seq
RNA m5C methylation profile of MCF10A and MDA486 by using MeRIP-Seq protocol Immunoprecipitation of Methylated mRNA at Cytosine (m5C) residues: Affinity purified of anti-methyl cytosine (m5C) polyclonal antibody 7ug (Zymo Research, Catalog#A3001-50) was conjugated with protein-A magnetic beads for 2...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-53370 | biostudies-arrayexpress
Proteomicsm5C RNA methylation modified or unmodified DNA:RNA hybrids pulldown
The biotin labeled DNA:RNA hybrids with or without RNA m5C modification were incubated with lysates of 293 cells treated with H2O2, and were pulled down by Streptavidin. The proteins pulled down by the empty beads control, unmodified or m5C-modified hybrids were analyzed by mass spectrometry
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-04-29 | MSV000089337 | MassIVE
GenomicsTranscriptome-Wide M5C Methylation Profiling in NSUN6-Knockdown HepG2 Cells
Transcriptome-Wide M5C Methylation Profiling in NSUN6-Knockdown HepG2 Cells
PRJNA1294392 | ENA
GenomicsLoss of cytosine-5 methylation in tRNA triggers stress responses in a disease model for Intellectual Disability
Mutations in the cytosine-5 RNA methyltransferase NSun2 can cause Intellectual Disability (ID) and symptoms commonly found in patients with Dubowitz syndrome. By analysing gene expression data with the global cytosine-5 RNA methylome in NSun2-deficient mice, we find that loss of cytosine-5 RNA met...
ORGANISM(S): Mus musculus 
2014-11-06 | E-GEOD-44746 | biostudies-arrayexpress
GenomicsGenome-wide maps of m5C methylation in neuron of mouse.
Genome-wide maps of m5C methylation in neuron of mouse.
PRJNA693829 | ENA
UnknownRNA m5C methylation orchestrates BLCA progression via macrophage reprogramming.
Not available
S-EPMC10424284 | biostudies-literature
GenomicsMicroarray detection of m5C RNA methylation modification in human lung cancer tissues
Microarray detection of m5C RNA methylation modification in human lung cancer tissues
PRJNA971532 | ENA
GenomicsProfiling of 5-methylcytosine (m5C) methylation in E14 cell line with siControl and siNsun2
Profiling of 5-methylcytosine (m5C) methylation in E14 cell line with siControl and siNsun2
PRJNA909590 | ENA
UnknownNSUN2-mediated HCV RNA m5C Methylation Facilitates Viral RNA Stability and Replication.
Not available
S-EPMC12233092 | biostudies-literature
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