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TranscriptomicsPlasma miRNA profile as a predictor for early virological response of interferon treatment in chronic hepatitis B patients
To find novel circulating markers associated with prognosis of interferon therapy,We performed microarray analysis of plasma samples in 94 chronic hepatitis B patients Ninety four HBV patients, who underwent PEG-IFN or conventional interferon treatment were enrolled. Their plasma samples before trea...
ORGANISM(S): Homo sapiens 
2011-09-19 | E-GEOD-29911 | biostudies-arrayexpress
ProteomicsMyocardial Injury Caused by Chronic Alcohol Exposure——A Pilot Study Based on Proteomic
Chronic alcohol exposure can cause myocardial degenerative diseases, manifested as cardiac insufficiency, arrhythmia, etc. These are defined as alcoholic cardiomyopathy (ACM). Alcohol-mediated myocardial injury has previously been studied through metabolomics, and it has been proved to be involved i...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD032949 | Pride
Alcoholic cardiomyopathy  proteomics  differentially expressed proteins  kegg pathway  myocardial injury 
ProteomicsAlterations of human plasma proteome profile on adaptation to high-altitude hypobaric hypoxia
For individuals migrating to or residing permanently at high-altitude regions, environmental hypobaric hypoxia is a primary challenge which induces several physiological or pathological responses. It is well documented that human beings adapt to hypobaric hypoxia via some protective mechanisms, such...
ORGANISM(S): Homo sapiens (Human) 
2019-03-27 | PXD012221 | Pride
Proteomics  high altitude  hypobaric hypoxia  complement and coagulation cascades  antioxidant  glycolysis. 
ProteomicsProteome-wide lysine succinylome profiling and comprehensive analysis of protein lysine co-modification in developing rice seeds
Lysine succinylation has been recognized as a post-translational modification (PTM) in recent years. It is plausible that succinylation may have a vaster functional impact than acetylation due to bulkier structural changes and greater charge differences on the modified lysine residue. Currently, how...
ORGANISM(S): Oryza sativa (Rice) 
2019-09-09 | PXD013664 | Pride
Post-translational modification  lysine succinylation  succinylome  rice  storage nutrient  seeds 
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