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TranscriptomicsDirect reprogramming of human fibroblasts to functional hepatocyte-like cells
Plasticity of differentiated cells has been proved by nuclear transfer, induced pluripotent cells and transdifferentiation. Here we show that by transduction of 3 factors (FOXA3, HNF1A and HNF4A), human fetal fibroblasts can be converted to hepatocyte-like cells (hiHep cells), expressing hepatic mar...
ORGANISM(S): Homo sapiens 
2014-03-06 | E-GEOD-42643 | biostudies-arrayexpress
TranscriptomicsIdentifying PD0325901-regulated genes in the J1 mESCs
It has been demonstrated that PD0325901 promotes self-renewal of mouse embryonic stem cells, however, the target genes of PD0325901 are not fully understood. To better understand the downstream target genes of PD0325901, we performed Microarray analyses to identify their downstream targets. The data...
ORGANISM(S): Mus musculus 
2016-05-17 | E-GEOD-67534 | biostudies-arrayexpress
TranscriptomicsIdentifying CHIR99021 and AICAR-regulated genes in the J1 mESCs
It has been demonstrated that CHIR99021 promotes self-renewal of mouse embryonic stem cells, however, the target genes of CHIR99021 is not fully understood. AICAR is the activator of AMP-activated protein kinase. It is reported that AICAR plays important role in mouse embryonic stem cells, however t...
ORGANISM(S): Mus musculus 
2013-01-01 | E-GEOD-40959 | biostudies-arrayexpress
TranscriptomicsIdentifying vitamin C and RA-regulated genes in the J1 mESCs
It has been demonstrated that vitamin C enhances reprogramming efficiency during inducing pluripotent stem cells, however, the underlying mechanisms are not fully understood. To find the downstream target genes of vitamin C and investigate the mechanism of vitamin C on reprogramming promotion, we pe...
ORGANISM(S): Mus musculus 
2014-01-21 | E-GEOD-43405 | biostudies-arrayexpress
ProteomicsG3BP orthologs interactional network
G3BP orthologs interactional network in humans and species.
ORGANISM(S): Homo Sapiens Drosophila Melanogaster Caenorhabditis Elegans 
2024-08-08 | PXD054692 |
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