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MetabolomicsSimultaneously discovering the fate and biochemical effects of pharmaceuticals through untargeted metabolomics
Untargeted metabolomics is an established approach in toxicology for characterising endogenous metabolic responses to xenobiotic exposure. Detecting the xenobiotic and its biotransformation products as part of the metabolomics analysis provides an opportunity to simultaneously gain deep insights int...
2023-07-03 | MTBLS2746 | MetaboLights
TranscriptomicsModulation of murine bone marrow derived dendritic cells by IL-4
The archetypal Th2 cytokine interleukin 4 (IL-4) has previously been shown to alternatively activate dendritic cells (DCs) both in vitro and in vivo.To more fully understand the impact of IL-4 dependent alternative activation of DCs, we used mRNA microarrays to define their transcriptional profile. ...
ORGANISM(S): Mus musculus 
2015-04-28 | E-GEOD-59868 | biostudies-arrayexpress
UnknownPersistent Functional Decline Following Hospitalization with Influenza or Acute Respiratory Illness.
Not available
S-EPMC7984066 | biostudies-literature
UnknownThe 2018 Lake Louise Acute Mountain Sickness Score.
Not available
S-EPMC6191821 | biostudies-literature
UnknownAssociations of work hours with carotid intima-media thickness and ankle-brachial index: the Multi-Ethnic Study of Atherosclerosis (MESA).
Not available
S-EPMC4084707 | biostudies-literature
TranscriptomicsRNA-seq of C57BL/6J female mouse ovaries, hypothalamus, and pituitary gland tissue in animals infected with Trypanosoma brucei brucei at acute and chronic time points
Data from our group has shown that the protozoan parasite Trypanosoma brucei brucei can invade the mouse female reproductive tract (FRT) causing changes in tissue architecture and immune profile, as well as inducing reproductive cycle arrest. The purpose of this experiment was to identify transcript...
ORGANISM(S): Mus musculus 
2026-09-07 | E-MTAB-17174 | biostudies-arrayexpress
UnknownHuntington's disease LIG1 modifier variant increases ligase fidelity and suppresses somatic CAG repeat expansion.
Not available
S-EPMC12338604 | biostudies-literature
GenomicsA dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells [ChIP-Seq]
Dendritic cells (DCs) direct CD4+ T cell differentiation into distinct T helper (Th) subsets that are vital for protection against diverse types of infection. However, the mechanisms employed by DCs to initiate Th2 responses, which are important for immunity to helminth infection as well as being a...
ORGANISM(S): Mus musculus 
2015-04-20 | E-GEOD-66198 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of adult male whole MutaMouse lung with its immortalized 100% confluent epithelial lung cell line counterpart (agilent array)
Biological comparison of gene expression profiles of adult male whole Muta?Mouse lung with its immortalized 100% confluent epithelial lung cell line counterpart. White, P.A.,et al. 2003. Development and characterization of an epithelial cell line from Muta?Mouse lung. Environ Mol Mutagen 42,3 pgs...
ORGANISM(S): Mus musculus 
2004-07-01 | E-MEXP-111 | biostudies-arrayexpress
TranscriptomicsAn integrated genetic-epigenetic analysis of schizophrenia: Evidence for co-localization of genetic associations and differential DNA methylation.
Abstract Background: Schizophrenia is a severe, highly heritable, neuropsychiatric disorder characterized by episodic psychosis and altered cognitive function. Despite success in identifying genetic variants associated with schizophrenia, there remains uncertainty about the causal genes involved in...
ORGANISM(S): Homo sapiens 
2016-08-01 | E-GEOD-84727 | biostudies-arrayexpress
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