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TranscriptomicsTranscription profiling of mouse FACS-purified cortical projection neurons using Affymetrix 430 2.0 microarrays
3 subtypes of cortical projection neurons were purified by fluorescence-activated cell sorting (FACS) at 4 different stages of development from mouse cortex. A detailed description of the data set is described in Arlotta, P et al (2005) and Molyneaux, BJ et al (2009). The hybridization cocktails use...
ORGANISM(S): Mus musculus 
2009-10-09 | E-GEOD-17783 | biostudies-arrayexpress
TranscriptomicsmiR-206 integrates multiple components of differentiation pathways to control the transition from growth to differentiation in rhabdomyosarcoma cells (miRNA)
Background: Similar to replicating myoblasts, many rhabdomyosarcoma cells express the myogenic determination gene MyoD. In contrast to myoblasts, rhabdomyosarcoma cells do not make the transition from a regulative growth phase to terminal differentiation. Previously we demonstrated that the forced e...
ORGANISM(S): Homo sapiens 
2012-04-01 | E-GEOD-35606 | biostudies-arrayexpress
TranscriptomicsmiR-206 integrates multiple components of differentiation pathways to control the transition from growth to differentiation in rhabdomyosarcoma cells
This SuperSeries is composed of the following subset Series: GSE35491: miR-206 integrates multiple components of differentiation pathways to control the transition from growth to differentiation in rhabdomyosarcoma cells (Illumina) GSE35606: miR-206 integrates multiple components of differentiation ...
ORGANISM(S): Homo sapiens 
2012-04-01 | E-GEOD-35921 | biostudies-arrayexpress
TranscriptomicsmiR-206 integrates multiple components of differentiation pathways to control the transition from growth to differentiation in rhabdomyosarcoma cells (Illumina)
Background: Similar to replicating myoblasts, many rhabdomyosarcoma cells express the myogenic determination gene MyoD. In contrast to myoblasts, rhabdomyosarcoma cells do not make the transition from a regulative growth phase to terminal differentiation. Previously we demonstrated that the forced e...
ORGANISM(S): Homo sapiens 
2012-04-01 | E-GEOD-35491 | biostudies-arrayexpress
TranscriptomicsComparison of Genome-Wide Binding of MyoD in Normal Human Myogenic Cells and Rhabdomyosarcomas Identifies Regional and Local Suppression of Promyogenic Transcription Factors (MyoD ChIP-Seq profiling).
Rhabdomyosarcoma is a pediatric tumor of skeletal muscle that expresses the myogenic basic helix-loop-helix protein MyoD but fails to undergo terminal differentiation. Prior work has determined that DNA binding by MyoD occurs in the tumor cells, but myogenic targets fail to activate. Using MyoD chro...
ORGANISM(S): Homo sapiens 
2013-08-29 | E-GEOD-50411 | biostudies-arrayexpress
GenomicsComparison of Genome-Wide Binding of MyoD in Normal Human Myogenic Cells and Rhabdomyosarcomas Identifies Regional and Local Suppression of Promyogenic Transcription Factors (expression profiling).
Rhabdomyosarcoma is a pediatric tumor of skeletal muscle that expresses the myogenic basic helix-loop-helix protein MyoD but fails to undergo terminal differentiation. Prior work has determined that DNA binding by MyoD occurs in the tumor cells, but myogenic targets fail to activate. Using MyoD chro...
ORGANISM(S): Homo sapiens 
2013-08-29 | E-GEOD-50413 | biostudies-arrayexpress
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