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TranscriptomicsRibose utilization by the human commensal Bifidobacterium breve UCC2003
Growth of B. breve UCC2003 on ribose leads to the transcriptional induction of the rbsACBDK gene cluster. Generation and phenotypic analysis of an rbsA insertion mutant established that the rbs gene cluster is essential for ribose utilization, and that its transcription is likely regulated by a LacI...
ORGANISM(S): Bifidobacterium breve UCC2003 
2010-05-19 | E-GEOD-17325 | biostudies-arrayexpress
TranscriptomicsRegulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut
Alterations in the gastrointestinal microbiota have been implicated in obesity in mice and humans, but the conserved microbial functions that influence host energy metabolism and adiposity have not been determined. Here we show that bacterial bile salt hydrolase (BSH) controls a microbe-host dialogu...
ORGANISM(S): Mus musculus 
2014-05-09 | E-GEOD-46952 | biostudies-arrayexpress
TranscriptomicsChanges in the gene transcription of Lactobacillus salivarius UCC118 in response to coculture with caco-2 epithelial cells
Lactobacillus salivarius UC118 was exposed to caco-2 epithelial cells for 1.5 hours. The total RNA was extracted from the coculture transcribed to cDNA and labelled. RNA was also extractred from UCC118 cells that were not exposed to caco-2 cells, transcribed to cDNA and labelled. Differences between...
ORGANISM(S): Lactobacillus salivarius 
2012-07-27 | E-MEXP-3607 | biostudies-arrayexpress
TranscriptomicsAdhesion and bacteriocin production by Lactobacillus salivarius influence the intestinal epithelial cell transcriptional response
The effect of epithelial cell-bacterial interaction on gene transcription in the epithelial cells and bacterial cells in vitro. The transcriptional response elicited by the UCC118 sortase deletion mutant will be compared to that of the wild type UCC118.
ORGANISM(S): Homo sapiens 
2012-07-27 | E-MEXP-3616 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression in UCC118 with gene expression in the UCC118 dSrtA mutant following exposure to Caco2 cells
This experiment compared the gene expression profiles of Lactobacillus salivarius UCC118 (wild type, control) and UCC118 with the SrtA gene deleted. Following exposure of both strains to Caco-2 epithelial cells.
ORGANISM(S): Lactobacillus salivarius 
2012-07-27 | E-MEXP-3614 | biostudies-arrayexpress
TranscriptomicsComparison of gene transcription in Caco-2 cells stimulated with Lactobacillus salivarius UCC118 with that in unstimulated cells.
Effect of Lactobacillus salivarius on gene transcription in caco-2 epithelial cells.
ORGANISM(S): Homo sapiens 
2012-07-27 | E-MEXP-3597 | biostudies-arrayexpress
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