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GenomicsDNA double-strand breaks induced by high NaCl occur predominantly in gene deserts
High concentration of NaCl increases DNA breaks both in cell culture and in vivo. The breaks remain elevated as long as NaCl concentration remains high and are rapidly repaired when the concentration is lowered. Repair of the breaks after NaCl is reduced is accompanied by formation of foci containi...
ORGANISM(S): Mus musculus 
2011-11-21 | E-GEOD-32882 | biostudies-arrayexpress
UnknownSouthwest Oncology Group S0802: a randomized, phase II trial of weekly topotecan with and without ziv-aflibercept in patients with platinum-treated small-cell lung cancer.
Not available
S-EPMC4121504 | biostudies-literature
TranscriptomicsSpinal Ependymoma Gene Expression Data
Purpose: Myxopapillary ependymoma (MPE) is a distinct histological variant of ependymoma arising commonly in the spinal cord. Despite an overall favorable prognosis, distant metastases, subarachnoid dissemination, and late recurrences have been reported. Currently the only effective treatment for M...
ORGANISM(S): Homo sapiens 
2015-09-02 | E-GEOD-66787 | biostudies-arrayexpress
UnknownTwo novel Pleosporales species isolated from the bark of Acer saccharum.
Not available
S-EPMC11317865 | biostudies-literature
ProteomicsUpdating the Proteome of the uncultivable hemotrophic Mycoplasma suis in experimentally infected pigs
Mycoplasma suis belongs to the hemotrophic mycoplasma (HM) that are associated with acute and chronic anemia in a wide range of livestock and wild animals. The inability to culture HMs in vitro has hindered their characterization at the molecular level. Although genome sequences of eight HMs are ava...
ORGANISM(S): Mycoplasma suis (strain KI_3806) Sus scrofa domesticus (domestic pig) 
2015-12-17 | PXD002294 | Pride
Mycoplasma suis 
UnknownPhase II selection design trial of concurrent chemotherapy and cetuximab versus chemotherapy followed by cetuximab in advanced-stage non-small-cell lung cancer: Southwest Oncology Group study S0342.
Not available
S-EPMC3020704 | biostudies-literature
TranscriptomicsTranscription forms and remodels supercoiling domains unfolding large scale chromatin structures [NimbleGen ChIP-chip]
This study was designed to investigate DNA supercoiling across the human genome and to understand how supercoiling domains impact on higher levels of genome organisation. DNA supercoiling is an inherent consequence of twisting DNA and is critical for regulating gene expression and DNA replication. H...
ORGANISM(S): Homo sapiens 
2013-02-17 | E-GEOD-43448 | biostudies-arrayexpress
UnknownApproaches to Recruitment of Postmenopausal Women for a Community-Based Study.
Not available
S-EPMC6602805 | biostudies-literature
TranscriptomicsTranscription forms and remodels supercoiling domains unfolding large scale chromatin structures [Agilent ChIP-chip]
This study was designed to investigate DNA supercoiling across the human genome and to understand how supercoiling domains impact on higher levels of genome organisation. DNA supercoiling is an inherent consequence of twisting DNA and is critical for regulating gene expression and DNA replication. H...
ORGANISM(S): Homo sapiens 
2013-02-17 | E-GEOD-43450 | biostudies-arrayexpress
TranscriptomicsBleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: A model for “active” disease.
Genomic profiling of bleomycin- and saline-treated mice across 7 timepoints (1, 2, 7, 14, 21, 28, 35 days post treatment) was carried out in C57BL6/J mice to determine the phases of response to bleomycin treatment which correspond to onset of active pulmonary fibrosis. Temporal genomic characterizat...
ORGANISM(S): Mus musculus 
2013-04-10 | E-GEOD-40151 | biostudies-arrayexpress
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