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ProteomicsDeep Dive in the Proteome of Human Cerebrospinal Fluid: A Valuable Data Resource for Biomarker Discovery and Missing Protein Identification
Cerebrospinal fluid (CSF) is a body fluid of choice for biomarker studies of brain disorders but remains relatively under-studied compared to other biological fluids such as plasma, partly due to the more invasive means of its sample collection. The present study establishes an in-depth CSF proteome...
ORGANISM(S): Homo sapiens (Human) 
2018-08-29 | PXD009646 | Pride
Augurin  brain  cerebrospinal fluid  human proteome project  mass spectrometry  proteomics  missing proteins  tandem mass tag 
ProteomicsDeep Dive in the Proteome of Human Cerebrospinal Fluid: A Valuable Data Resource for Biomarker Discovery and Missing Protein Identification
Cerebrospinal fluid (CSF) is a body fluid of choice for biomarker studies of brain disorders but remains relatively under-studied compared to other biological fluids such as plasma, partly due to the more invasive means of its sample collection. The present study establishes an in-depth CSF proteome...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-12 | MSV000083965 | MassIVE
ProteomicsExploration of human cerebrospinal fluid: A large proteome dataset revealed by trapped ion mobility time-of-flight mass spectrometry
Cerebrospinal fluid (CSF) is a biofluid in direct contact with the brain and as such constitutes a sample of choice in the study of neurological disorders, including neurodegenerative diseases such as Alzheimer or Parkinson. Human CSF has still been less studied using proteomic technologies compared...
ORGANISM(S): Homo sapiens (Human) 
2020-05-07 | PXD018369 | Pride
Proteomics Mass spectrometry Large-scale proteome Cerebrospinal fluid Lc-ms/ms 
ProteomicsAn adaptive pipeline to maximize isobaric tagging data in large-scale MS-based proteomics
Isobaric tagging is a method of choice in Mass Spectrometry (MS)-based proteomics for comparing multiple conditions at a time. Despite its multiplexing capabilities, when multiple experiments are merged for comparison in large sample-size studies, some drawbacks appears, due to the presence of missi...
ORGANISM(S): Homo sapiens (Human) 
2018-05-01 | PXD008029 | Pride
Algorithms  bioinformatics  biomarkers  discovery  isobaric tagging  machine learning  protein identification  quantification  tandem mass spectrometry  tandem mass tag 
ProteomicsQuest for missing proteins in the human spermatozoa: an update
Here, we report work as part of C-HPP initiatives on chromosomes 14 (France) and 2 (Switzerland) aiming to identify missing proteins in ejaculated human spermatozoa using multiple MS-based and antibodies-based validation approaches
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080826 | MassIVE
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