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TranscriptomicsReversal of persistent wound-induced retinal pigmented epithelial-to-mesenchymal transition by the TGFb pathway inhibitor, A-83-01.
Age-related macular degeneration (AMD) is a leading cause of blindness. Most vision loss occurs following the transition from a disease of deposit formation and inflammation to a disease of neovascular fibrosis and/or cell death. Here, we investigate how repeated wound stimulus leads to seminal chan...
ORGANISM(S): Homo sapiens 
2015-07-06 | E-GEOD-67898 | biostudies-arrayexpress
UnknownIntravitreal aflibercept for diabetic macular edema: structural and functional improvements.
Not available
S-EPMC11880015 | biostudies-literature
UnknownMultimodal imaging evaluation of occult macular dystrophy associated with a novel RP1L1 variant.
Not available
S-EPMC9058645 | biostudies-literature
Proteomics• Clinical proteomics profiling for biomarker identification among patients suffering with Indian Post Kala Azar Dermal Leishmaniasis
Post Kala Azar Dermal Leishmaniasis (PKDL) is a non-fatal dermal sequel of Visceral Leishmaniasis (VL), caused by protozoan parasite Leishmania donovani. On the global scenario, PKDL in mainly restricted to distinct zones of South Asia (India, Nepal and Bangladesh) and East Africa, mainly Sudan. In ...
ORGANISM(S): Homo sapiens (Human) 
2020-05-20 | PXD012960 | Pride
Cured (p4) Healthy (p1) Macular (p2) Post kala azar dermal leishmaniasis Circulating immune complexes Polymorphic (p3) Proteomics Biomarker 
UnknownComparative Study of a Modified Sub-Tenon's Capsule Injection of Triamcinolone Acetonide and the Intravenous Infusion of Umbilical Cord Mesenchymal Stem Cells in Retinitis Pigmentosa Combined With Macular Edema.
Not available
S-EPMC8503560 | biostudies-literature
TranscriptomicsIdentification of cell surface markers and establishment of monolayer differentiation protocol for retinal pigment epithelial cells.
In vitro differentiation of human pluripotent stem cells into functional retinal pigment epithelial (RPE) cells for cell based reparative therapy of age-related macular degeneration (AMD). In the present study, we identify CD140b, CD56, GD2 and CD184 as central cell surface markers to evaluate hPSC-...
ORGANISM(S): Homo sapiens 
2020-02-29 | E-MTAB-7742 | biostudies-arrayexpress
TranscriptomicsRNAseq analysis of the global retinal transcriptome of rod photoreceptor-specific Dicer1 conditional knockout mice and control littermates
We report RNAseq analysis of the transcriptome of retinas from mature rod-specific Dicer1 cKO mice and control littermates lacking Cre expression in order to better understand changes in gene regulation that could lead to retinal degeneration in cKO mice. Examine retinal transcriptome of 3 biologica...
ORGANISM(S): Mus musculus 
2014-08-14 | E-GEOD-55377 | biostudies-arrayexpress
TranscriptomicsAnalysis of the global retinal transcriptome of rod photoreceptor-specific Dicer1 conditional knockout mice and control littermates
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-08-14 | E-GEOD-55393 | biostudies-arrayexpress
TranscriptomicsComparison of Glomerular Transcriptome Profiles of Adult-Onset Steroid Sensitive Focal Segmental Glomerulosclerosis and Minimal Change Disease
To search for biomarkers to differentiate Adult-Onset Steroid Sensitive focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD). Compared the profiles of glomerular transcriptomes between patients with FSGS and patients with MCD using microarray analysis. This dataset is part of ...
ORGANISM(S): Homo sapiens 
2017-01-04 | E-GEOD-69814 | biostudies-arrayexpress
ProteomicsA framework for quality control in quantitative proteomics
A thorough evaluation of the quality, reproducibility, and variability of bottom-up proteomics data is necessary at every stage of a workflow, from planning to analysis. We share vignettes applying adaptable quality control (QC) measures to assess sample preparation, system function, and quantitativ...
ORGANISM(S): Homo Sapiens Mus Musculus Bos Taurus Saccharomyces Cerevisiae 
PXD051318 | panorama
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