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GenomicsPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [RRBS]
We report a reprogrammable mouse system in which reprogramming factor expression in vivo can be controlled temporally by treatment with doxycycline (Dox). Transient expression of reprogramming factors in vivo results in tumor development in various tissues, consisting of undifferentiated dysplastic...
ORGANISM(S): Mus musculus 
2014-02-13 | E-GEOD-52303 | biostudies-arrayexpress
TranscriptomicsPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
We report a reprogrammable mouse system in which reprogramming factor expression in vivo can be controlled temporally by treatment with doxycycline (Dox). Transient expression of reprogramming factors in vivo results in tumor development in various tissues, consisting of undifferentiated dysplastic...
ORGANISM(S): Mus musculus 
2014-02-13 | E-GEOD-51786 | biostudies-arrayexpress
ProteomicsProteome analysis of GCN1 CKO mouse liver
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the liver, we compared the whole cell proteome of livers harvested from GCN1 CKO mice with that of wild-type mice.
ORGANISM(S): Mus Musculus (mouse) 
2023-04-01 | PXD030514 | JPOST Repository
ProteomicsProteome analysis of GCN1 CKO mouse ileum
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the intestinal epithelium, we compared the whole cell proteome of ileum harvested from GCN1 CKO mice with that of wild-type m...
ORGANISM(S): Mus Musculus (mouse) 
2024-03-31 | PXD030518 | JPOST Repository
ProteomicsProteome analysis of GCN1 CKO mouse duodenum
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the intestinal epithelium, we compared the whole cell proteome of duodenum harvested from GCN1 CKO mice with that of wild-typ...
ORGANISM(S): Mus Musculus (mouse) 
2024-03-31 | PXD030517 | JPOST Repository
ProteomicsProteome analysis of GCN1 CKO mouse inguinal white adipose tissue (iWAT)
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the inguinal white adipose tissue (iWAT), we compared the whole cell proteome of eWAT harvested from GCN1 CKO mice with that ...
ORGANISM(S): Mus Musculus (mouse) 
2024-03-31 | PXD030516 | JPOST Repository
ProteomicsProteome analysis of GCN1 CKO mouse jejunum
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the intestinal epithelium, we compared the whole cell proteome of jejunum harvested from GCN1 CKO mice with that of wild-type...
ORGANISM(S): Mus Musculus (mouse) 
2022-08-29 | PXD030519 | JPOST Repository
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