Sort   by:  
 Page size 
TranscriptomicsExpression Profiles of HepG2 cells treated with genotoxic and non-genotoxic agents
The lack of accurate in vitro assays for predicting in vivo toxicity of chemicals together with new legislations demanding replacement and reduction of animal testing has triggered the development of alternative methods. This study aimed at developing a transcriptomics-based in vitro prediction assa...
ORGANISM(S): Homo sapiens 
2012-08-02 | E-GEOD-28878 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human HepG2 cells treated with false positive genotoxins, true genotoxins and non-genotoxins
In this study we aimed to identify the molecular pathways modified by the false positive genotoxins Quercetin, 8-Hydroxyquinoline and 17beta-Estradiol that may explain their in vitro genotoxic and their in vivo non-genotoxic effects, by combining in vitro transcriptomics with phenotypic data. The ef...
ORGANISM(S): Homo sapiens 
2011-01-01 | E-MEXP-2574 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human HepG2 cells treated with TCDD
The integration of different M-^SomicsM-^T technologies has already been shown in several in vivo studies to offer a complementary insight into cellular responses of toxic processes. We therefore hypothesize that the combining of transcriptomics and metabonomics data may improve the understanding of...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-MEXP-2817 | biostudies-arrayexpress
UnknownIntegrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells.
Not available
S-EPMC3231768 | biostudies-literature
TranscriptomicsTranscription profiling of human hepatoma cell lines HepG2 and HepaRG using whole genome gene expression analysis before and after exposure to the GTX carcinogens AFB1 and BaP, and the NGTX carcinogens CsA, E2 and TCDD for 12 and 48 h
Direct comparison of the hepatoma cell lines HepG2 and HepaRG using whole genome gene expression analysis before and after exposure to the GTX carcinogens AFB1 and BaP and the NGTX carcinogens CsA, E2 and TCDD for 12 and 48 h.
ORGANISM(S): Homo sapiens 
2010-04-15 | E-MEXP-2458 | biostudies-arrayexpress
Sort   by:  
 Page size