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ProteomicsComparative platelet releasate proteome profiling of acute coronary syndrome versus stable coronary artery disease
Upon activation, platelets release a host of soluble and vesicular signals, collectively termed the ‘platelet releasate’ (PR). The contents of this PR play a significant role in haemostasis, inflammation, and pathologic sequelae. Despite this, proteomic studies investigating the PR in coronary arter...
ORGANISM(S): Homo sapiens (Human) 
2020-06-05 | PXD009356 | Pride
Platelet releasate Proteomics Platelets Acute coronary syndrome Stable coronary artery disease Lc-ms/ms 
TranscriptomicsTreatment of CHRF288-11 Megakaryocytic Cells with Wnt compounds
CHRF288-11 cells were treated with Wnt3a (150ng/ml) and/ot Wnt5a (1200ng/ml) and RNA was harvested after 8 hours of treatment Gene expression was analysed using Human WG6 V3 Illumina Beadarrays There are four experimental groups (Wnt3a Treated, Wnt5a Treated, Wnt3a + Wnt5a treated and Untreated (con...
ORGANISM(S): Homo sapiens 
2012-11-07 | E-GEOD-42071 | biostudies-arrayexpress
Genomics58BC - samples
WTCCC2 samples from 1958 British Birth Cohort
EGAD00010000234 | EGA
GenomicsT2D - samples
WTCCC2 samples from Type 2 Diabetes Cohort
EGAD00010000232 | EGA
GenomicsHT - samples
WTCCC2 samples from Hypertension Cohort
EGAD00010000230 | EGA
GenomicsCAD - samples
WTCCC2 samples from Coronary Artery Disease Cohort
EGAD00010000236 | EGA
GenomicsAssociation studies using the Metabochip array - Samples analysed by the WTCCC (1958 British Birth Cohort (58BC), Hypertension cohort (HT), Type 2 Diabetes Cohort (T2D) and Coronary Artery Disease (CAD) cohort)
Genomewide association studies (GWAS) have proven a powerful hypothesis-free method to identify common disease-associated variants. Even quite large GWAS, however, have only at best identified moderate proportions of the genetic variants contributing to disease heritability. To provide cost-effectiv...
EGAS00000000115 | EGA
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