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TranscriptomicsReversal of Aberrant Cancer Methylome and Transcriptome upon Direct Reprogramming of Lung Cancer Cells.
This SuperSeries is composed of the following subset Series: GSE35911: Reversal of Aberrant Cancer Methylome and Transcriptome upon Direct Reprogramming of Lung Cancer Cells [Expression] GSE35912: Reversal of Aberrant Cancer Methylome and Transcriptome upon Direct Reprogramming of Lung Cancer Cells ...
ORGANISM(S): Homo sapiens 
2012-08-27 | E-GEOD-35913 | biostudies-arrayexpress
TranscriptomicsMutated RNA component of the telomerase induces apoptosis via GADD45-? in hTERT-overexpressing primary fibroblasts
Mutant template human telomerase RNAs (MT-hTers) have been shown to induce apoptosis in various cancerous cells that have high telomerase activity. However, the exact mechanisms by which MT-hTers inhibit the growth of cancer cells and affect normal somatic cells remain largely unknown. To determine ...
ORGANISM(S): Homo sapiens 
2011-05-28 | E-GEOD-24975 | biostudies-arrayexpress
TranscriptomicsInvestigation of extra-telomeric effects of hTERT in neoplastic transformation of IMR90 cells
The complexity and heterogeneity of cancer cells are under-represented by the current experimental models which revolve around primary tumor cells, cancer cell lines, and rodent models. We used the transformed cell model in our studies. IMR90 and BJ fibroblast cells were transformed by three oncogen...
ORGANISM(S): Homo sapiens 
2010-12-31 | E-GEOD-24097 | biostudies-arrayexpress
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