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TranscriptomicsUnique gene program of rat mesenteric arteries as revealed by Deep RNA Sequencing
This study used Deep RNA sequencing to define gene expression in the small resistance arteries and compare to a reference conduit artery, the aorta Methods: Deep RNA Sequencing (~90 million reads) was performed on 2 samples of adult SD rat mesenteric arteries and compared to that of 2 samples of aor...
ORGANISM(S): Rattus norvegicus 
2015-07-13 | E-GEOD-64450 | biostudies-arrayexpress
TranscriptomicsCardiomyocyte specific plin5 over expression
Presence of ectopic lipid droplets (LDs) in cardiac muscle is associated to lipotoxicity and tissue dysfunction. However, presence of LDs in heart is also observed in physiological conditions, such as at times when cellular energy needs and energy production from mitochondria fatty acid (FA) ?-oxid...
ORGANISM(S): Mus musculus 
2013-02-09 | E-GEOD-44192 | biostudies-arrayexpress
TranscriptomicsMNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL
The phosphorylation of eIF4E1 at serine 209 by MNK1 or MNK2 has been shown to initiate oncogenic mRNA translation, a process that favours cancer development and maintenance. Here, we interrogate the MNK-eIF4E axis in diffuse large B-cell lymphoma (DLBCL) and show a distinct distribution of MNK1 and ...
ORGANISM(S): Homo sapiens 
2014-11-18 | E-GEOD-61691 | biostudies-arrayexpress
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