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MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights
UnknownClassification with the matrix-variate-t distribution.
Not available
S-EPMC7954198 | biostudies-literature
MetabolomicsContributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer

BACKGROUND Increasing evidence implicates microbiome involvement in the development and progression of pancreatic ductal adenocarcinoma (PDAC). Studies suggest that reflux of gut or oral microbiota can lead to colonization in the pancreas, resulting in dysbiosis that culminates ...

2023-08-09 | MTBLS7260 | MetaboLights
UnknownGenetic diversity and relationship of Indian cattle inferred from microsatellite and mitochondrial DNA markers.
Not available
S-EPMC4485874 | biostudies-literature
UnknownPan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance.
Not available
S-EPMC11421770 | biostudies-literature
UnknownElimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells.
Not available
S-EPMC10810082 | biostudies-literature
UnknownA Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice.
Not available
S-EPMC4035450 | biostudies-literature
UnknownTargeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer.
Not available
S-EPMC9925045 | biostudies-literature
UnknownKRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells.
Not available
S-EPMC10785700 | biostudies-literature
TranscriptomicsThe Translation Initiation Factor eIF3h Targets Specific Transcripts to Polysomes during Embryogenesis
We have sequenced the polysome-associated translating mRNAs from stage-matched wild-type and eif3ha morphant embryos at ~24 hpf stage to identify transcripts translationally regulated by eIF3ha. As a control, we have also sequenced total mRNAs from the stage-matched wild-type and eif3ha morphants as...
ORGANISM(S): Danio rerio 
2013-06-05 | E-GEOD-44584 | biostudies-arrayexpress
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