Sort   by:  
 Page size 
TranscriptomicsStudying relative gene expression in primary and xenograft CRC samples
To compare the gene expression profile in primary human colorectal cancer samples and samples passaged in mice for two generations Primary human CRC samples were implanted in mice and allowed to grow for 2 generations. The tumors were then excised and a relative expression profile was evaluated to s...
ORGANISM(S): Homo sapiens 
2014-11-22 | E-GEOD-63544 | biostudies-arrayexpress
TranscriptomicsStudying relative gene expression in Head and Neck (HNSCC) tumor under diverse culture conditions
To compare the gene expression profile in HNSCC tumor cultured under various conditions Primary human HNSCC tumor was cultured for upto 72 hours in presence of Autologous Serum and combination of Autologous Serum and Tissue metalloproteinases ; angiogeneesis and tissue associated microenvironment si...
ORGANISM(S): Homo sapiens 
2014-11-22 | E-GEOD-63545 | biostudies-arrayexpress
TranscriptomicsUnderstanding molecular mechanisms of Cetuximab insensitivity in Colorectal Cancer (CRC)
Mutational status of KRAS in CRC is used to aid patient stratification for Cetuximab treatment. However, only a subset (10-40%) of patients with wt KRAS respond. We analyzed 40 mCRC tumors for Cetuximab response using a functional ex vivo platform. In the subset of non-responsive tumors, mutational ...
ORGANISM(S): Homo sapiens 
2014-04-01 | E-GEOD-56386 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse inbred strains to identify germline cancer modifiers using parental strain expression mapping
Inherited genetic risk factors play an important role in cancer. However, other than cancer susceptibility genes found in familial cancer syndromes and inherited in a Mendelian fashion, little is known about modifier genes (germline variants that interact with each other and with environmental facto...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7270 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse prostate from AKT transgenic or wild type littermate controls treated with RAD001 (MTOR inhibition) or placebo reveals mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways reveals
Transgenic (Probasin driven Myr-AKT)or wild-type littermates were treated with RAD001 or placebo and sacrificed at 12 and 48 hours following the beginning of treatment
ORGANISM(S): Mus musculus 
2007-09-29 | E-GEOD-1413 | biostudies-arrayexpress
UnknownHigher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC11872607 | biostudies-literature
UnknownEmpagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC10957483 | biostudies-literature
UnknownBaricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis.
Not available
S-EPMC9333998 | biostudies-literature
UnknownHigher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC10156147 | biostudies-literature
Sort   by:  
 Page size