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TranscriptomicsGenome-wide analysis of mRNA expression alterations of mucosa associated lymphoid tissue lymphoma translocation gene 1 (Malt1) -/- or Wild Type (WT) Naïve T cells induced to differentiate into (T helper) Th1 or Th17 cells
Microarrays were used to examine gene expression changes at two time points following the induction of differentiation of Malt1 deficient Naive T cells into Th1 or Th17 cells. The present study aims to find the effect that Malt1 deficiency has on lineage specific T cell differentiation. Malt1 is a...
ORGANISM(S): Mus musculus 
2013-09-01 | E-GEOD-40931 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of mRNA expression alterations of sorted LysM-KI LSK cells versus control LSK cells
Microarrays were used to examine gene expression changes between bone marrow isolated haematopoeietic cell populations (LSK cells: Lin-Sca1+cKit+) populations of control and mutant (LysM-KI) mice. The LysM-KI mouse is a murine model which expresses an Idh1 (isocitrate dehydrogenase 1) mutation (I...
ORGANISM(S): Mus musculus 
2012-07-21 | E-GEOD-38589 | biostudies-arrayexpress
TranscriptomicsIdentification of heavily translated mRNAs in PRR16/Largen-overexpressing cells.
The hypothesis tested in the present study was that PRR16/Largen influences mRNA translation to control mammalian cell size. Results provide important information of the effects of PRR16/Largen on translation of particular sets of mRNAs encoding histones, mitochondrial, and vascular transport protei...
ORGANISM(S): Homo sapiens 
2014-01-28 | E-GEOD-54383 | biostudies-arrayexpress
GenomicsIdh1-R132H mutation increases murine hematopoietic progenitors and alters epigenetics.
Mutations in the IDH1 and IDH2 genes encoding isocitrate dehydrogenases are frequent in human glioblastomas1 and cytogenetically normal acute myeloid leukemias (AML)2. These alterations are gain-of-function mutations in that they drive the synthesis of the M-bM-^@M-^\oncometaboliteM-bM-^@M-^] R-2-hy...
ORGANISM(S): Mus musculus 
2012-07-22 | E-GEOD-38687 | biostudies-arrayexpress
UnknownDiffusion deep learning for brain age prediction and longitudinal tracking in children through adulthood
Not available
S-EPMC12247581 | biostudies-literature
TranscriptomicsUse of clinical chromosomal microarray in Chinese patients with autism spectrum disorder - implications of a copy number variation involving dpp10 (Perkin Elmer CGX)
Background Array-Comparative-Genomic-Hybridization (aCGH) is recommended as first-tier genetic test for children with autism spectrum disorder (ASD). However, result interpretation can be challenging as copy number variants (CNVs) in non-European ASD patients is not well studied. To address this lit...
ORGANISM(S): Homo sapiens 
2017-04-07 | E-MTAB-5672 | biostudies-arrayexpress
TranscriptomicsUse of clinical chromosomal microarray in Chinese patients with autism spectrum disorder - implications of a copy number variation involving dpp10 (CGX-12)
Background: Array-Comparative-Genomic-Hybridization (aCGH) is recommended as first-tier genetic test for children with autism spectrum disorder (ASD). However, result interpretation can be challenging as copy number variants (CNVs) in non-European ASD patients is not well studied. To address this li...
ORGANISM(S): Homo sapiens 
2017-04-07 | E-MTAB-5665 | biostudies-arrayexpress
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