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TranscriptomicsTargeting oncogene expression to endothelial cells induces proliferation of the myelo-erythroid lineage by repressing the notch pathway
Human oncogenes involved in the development of hematological malignancies have been widely used to model experimental leukemia. Here, we used the fli1 promoter in zebrafish to target the expression of oncogenic HRAS to endothelial cells, including the hemogenic endothelium and observed the developme...
ORGANISM(S): Danio rerio 
2013-09-19 | E-GEOD-41988 | biostudies-arrayexpress
UnknownIbuprofen and diclofenac treatments reduce proliferation of pancreatic acinar cells upon inflammatory injury and mitogenic stimulation.
Not available
S-EPMC5758389 | biostudies-literature
UnknownEnhanced proliferation of pancreatic acinar cells in MRL/MpJ mice is driven by severe acinar injury but independent of inflammation.
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S-EPMC6010442 | biostudies-literature
UnknownComparative Mutational Profiling of Hematopoietic Progenitor Cells and Circulating Endothelial Cells (CECs) in Patients with Primary Myelofibrosis.
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S-EPMC8534986 | biostudies-literature
UnknownThe Simultaneous Deletion of pH-Sensing Receptors GPR4 and OGR1 (GPR68) Ameliorates Colitis with Additive Effects on Multiple Parameters of Inflammation.
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S-EPMC11855581 | biostudies-literature
UnknownRT-qPCR versus Digital PCR: How Do They Impact Differently on Clinical Management of Chronic Myeloid Leukemia Patients?
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S-EPMC7670369 | biostudies-literature
UnknownMist1+ gastric isthmus stem cells are regulated by Wnt5a and expand in response to injury and inflammation in mice.
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S-EPMC10337481 | biostudies-literature
UnknownDevelopment of BCR-ABL1 Transgenic Zebrafish Model Reproducing Chronic Myeloid Leukemia (CML) Like-Disease and Providing a New Insight into CML Mechanisms.
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S-EPMC7922348 | biostudies-literature
UnknownClass I histone deacetylase inhibition improves pancreatitis outcome by limiting leukocyte recruitment and acinar-to-ductal metaplasia.
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S-EPMC5647184 | biostudies-literature
UnknownCase Report: Late Onset of Myelodysplastic Syndrome From Donor Progenitor Cells After Allogeneic Stem Cell Transplantation. Which Lessons Can We Draw From the Reported Case?
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S-EPMC7591784 | biostudies-literature
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