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MetabolomicsNoxa regulation of malate aspartate shuttle
Not available
ORGANISM(S): Homo sapiens 
ST000146 | MetabolomicsWorkbench
GenomicsLactate deficiency-induced early embryonic arrest is mitigated through malate-aspartate shuttle
Lactate deficiency-induced early embryonic arrest is mitigated through malate-aspartate shuttle
PRJNA1272488 | ENA
GenomicsA crucial role of the malate aspartate shuttle in metabolic reprogramming in TNF-induced SIRS
A crucial role of the malate aspartate shuttle in metabolic reprogramming in TNF-induced SIRS
PRJNA1334435 | ENA
TranscriptomicsA crucial role of the malate aspartate shuttle in metabolic reprogramming in TNF-induced SIRS
Tumor necrosis factor (TNF) causes a lethal systemic inflammatory response syndrome (SIRS) which is characterized by significant metabolic alterations. Based on liver RNA sequencing, we found that TNF impairs the malate-aspartate shuttle (MAS), an essential redox shuttle that transfers reducing equi...
ORGANISM(S): Mus musculus 
2025-09-30 | GSE309252 | GEO
TranscriptomicsLactate deficiency-induced early embryonic arrest is mitigated through malate-aspartate shuttle
During assisted reproductive technology (ART) procedure, approximately one third to half of the in vitro fertilization (IVF) derived embryos cannot reach the blastocyst stage, and about 10% arrest at the early cleavage stage. Early mammalian embryos obtain nutrients from maternal environment to fulf...
ORGANISM(S): Mus musculus 
2025-06-12 | GSE299062 | GEO
UnknownDeficiency of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis.
Not available
S-EPMC7690131 | biostudies-literature
UnknownThe Malate-Aspartate Shuttle supports thermogenic lipid mobilization in brown adipocytes.
Not available
S-EPMC12340843 | biostudies-literature
UnknownSIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growth.
Not available
S-EPMC4406655 | biostudies-literature
UnknownInhibition of the malate-aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion.
Not available
S-EPMC7234840 | biostudies-literature
UnknownGLUL Ablation Can Confer Drug Resistance to Cancer Cells via a Malate-Aspartate Shuttle-Mediated Mechanism.
Not available
S-EPMC6966511 | biostudies-literature
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