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UnknownFear of cancer recurrence in peritoneal malignancy patients following complete cytoreductive surgery (CCRS) and hyperthermic intraperitoneal chemotherapy (HIPEC): an observational study protocol.
Not available
S-EPMC8845210 | biostudies-literature
TranscriptomicsHuman lung epithelial cells progressed to malignancy through specific oncogenic manipulations
We have developed cdk4/hTERT-immortalized normal human bronchial epithelial cells (HBECs) to study lung cancer pathogenesis. By studying the oncogenic effect of common lung cancer alterations (p53, KRAS, and c-MYC) we demonstrate the ability of this model to characterize the stepwise transformation...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-40828 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human histologically normal breast tissues reveals proliferative genes dominate malignancy-risk gene signature
Analysis of 143 completely histologically-normal breast tissues resulted in the identification of a “malignancy risk” gene signature that may serve as a marker of subsequent risk of breast cancer development. Experiment Overall Design: RNA was extracted from microdissected frozen breast ti...
ORGANISM(S): Homo sapiens 
2009-03-15 | E-GEOD-10780 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy (testing dataset)
The epidermal specific ablation of Trp53 gene leads to the spontaneous development of aggressive tumors in mice through a process that is accelerated by the simultaneous ablation of Rb gene. Since alterations of p53-dependent pathway are common hallmarks of aggressive, poor prognostic human cancers,...
ORGANISM(S): Mus musculus 
2010-07-20 | E-GEOD-19616 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy (training dataset)
The epidermal specific ablation of Trp53 gene leads to the spontaneous development of aggressive tumors in mice through a process that is accelerated by the simultaneous ablation of Rb gene. Since alterations of p53-dependent pathway are common hallmarks of aggressive, poor prognostic human cancers,...
ORGANISM(S): Mus musculus 
2010-07-20 | E-GEOD-11990 | biostudies-arrayexpress
TranscriptomicsGene expression profile of canine mammary malignancy
Molecular mechanisms of the canine mammary malignancy. RNA isolated from canine mammary tumours of the 3rd grade of malignancy was pooled and hybrydized on the same microarray as RNA isolated from canine mammary tumours of the 1st grade of malignancy. Based on the results the "malignancy portra...
ORGANISM(S): Canis lupus familiaris 
2013-10-01 | E-GEOD-44033 | biostudies-arrayexpress
GenomicsA comprehensive genomic study of pediatric malignancy
A comprehensive genomic study of pediatric malignancy
PRJNA588315 | ENA
GenomicsA comprehensive genomic study of pediatric malignancy
A comprehensive genomic study of pediatric malignancy
PRJNA588314 | ENA
TranscriptomicsEts-domain transcription factor Ets21c and nuclear receptor Ftz-F1 are novel effectors of JNK promoting tumor malignancy
Cancer represents a complex family of diseases, characterized by the uncontrolled malignant growth of a particular cell type and by metastatic dissemination of these transformed cells to secondary sites. The hallmark tumor features emerge as a result of aberrant cellular signaling and pathological g...
ORGANISM(S): Drosophila melanogaster 
2015-11-04 | E-GEOD-65261 | biostudies-arrayexpress
GenomicsBiopsy bacterial signature can predict patient tissue malignancy
Biopsy bacterial signature can predict patient tissue malignancy
PRJEB55383 | ENA
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