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ChIP-seq of H3S10p in synchronized and asynchronous ESCs and RNA-seq of ESCs after inhibition of AURKB ChIP-seq of H3S10p and RNA-seq for ESCs treated with ZM-447439
ORGANISM(S): Mus musculus 
We assembled a quantitative map for the abundance and interactions of 16 factors related to PCH in living cells and found that stably bound complexes of the histone methyltransferase Suv39h1/2 demarcate the PCH state. From the experimental data we developed a predictive mathematical model that expla...
ORGANISM(S): Mus musculus 
The global impact of DNA methylation on alternative splicing is largely unknown. Using a genome-wide approach in wild-type and methylation-deficient embryonic stem cells, we found that DNA methylation can act both as an enhancer and as a silencer of splicing, and affects the splicing of more than 20...
ORGANISM(S): Mus musculus 
ICGC MMML-seq Data Freeze March 2013 transcriptome sequencing
DNA methylation analysis of 6 primary lymphoma samples
Whole Genome Seq: Illumina HiSeq sequence data (with >30x coverage) were aligned to the hg19 human reference genome assembly using BWA (Li and Durbin, 2009); duplicate reads were removed from the final BAM file. No realignment or recalibration was performed. Paired-end RNA sequencing reads were mapp...
ICGC MMML-seq Data Freeze July 2013 transcriptome sequencing
ICGC MMML-seq Data Freeze March 2013 whole genome sequencing
ICGC MMML-seq Data Freeze November 2012 whole genome sequencing
ICGC MMML-seq Data Freeze November 2012 transcriptome sequencing
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