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TranscriptomicsmRNA expression data from lymph node tumors from IL10R2-/- patients
Gene expression profiles were used to identify coordinately regulated gene sets and pathways actuvated in tumors occuring in IL10R2-/- patients. Frozen tumor biopsies and paired peripheral blood from 2 children with IBD and 2 age-matched tonsil were obtained. Cases were ascertained at the Necker hos...
ORGANISM(S): Homo sapiens 
2012-07-22 | E-GEOD-39503 | biostudies-arrayexpress
GenomicsSite- and allele-specific de-silencing of polycomb repressive activity by insertional oncogenesis: a new recurrent mechanism of TAL1 activation in T-ALL
T-cell acute lymphoblastic leukemia’s (T-ALL) are malignant proliferations of thymocytes occurring through a large diversity of genomic and epigenetic alteration. TAL1 is amongst the most frequently deregulated oncogenes. Known TAL1 dysregulation mechanisms consist of t(1;14) translocations and SIL...
ORGANISM(S): Homo sapiens 
2014-07-10 | E-GEOD-59257 | biostudies-arrayexpress
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