Sort   by:  
 Page size 
Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation
Transcriptional targets of neurogenin (Ngnr1) were identified by over-expression of an inducible form of neurogenin in Xenopus ectodermal explants. The effects of co-expressing the nucleoprotein geminin on Ngnr1-dependent target gene transactivation were defined. Regulating the transition from line...
ORGANISM(S): Xenopus laevis 
Neural stem cells (NSCs) in the adult mammalian subependymal zone maintain a glial identity and the developmental potential to generate neurons during the lifetime. Production of neurons from these NSCs is not direct but follows an orderly pattern of cell progression which allows the gradual increas...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-08 | PXD038983 | Pride
Regulating the transition from lineage-restricted progenitors to terminally differentiated cells is a central aspect of nervous system development. Here, we investigated the role of the nucleoprotein Geminin in regulating neurogenesis at a mechanistic level during both Xenopus primary neurogenesis a...
ORGANISM(S): Mus musculus 
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Xenopus laevis 
Neural stem cells (NSCs) generating new neurons are restricted to few niches in the adult mammalian brain, while the remainder rather promotes gliogenesis. Here we take advantage of the spatial separation of an NSC niche (the subependymal zone) and the region to where the newly generated neurons mig...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-27 | PXD016632 | Pride
The impact of timing and injury mode on induced neurogenesis in the adult mammalian retina
Sort   by:  
 Page size