Sort   by:  
 Page size 
Metabolomics1H NMR based urinary metabolites profiling dataset of canine mammary tumors

The identification of efficient and sensitive biomarkers for non-invasive tests is one of the major challenges in cancer diagnosis. To address this challenge, metabolomics is widely applied for identifying biomarkers that detects abnormal changes in cancer patients. Canine mammary tumors exhibit ...

2022-02-24 | MTBLS2550 | MetaboLights
TranscriptomicsTranscription profiling of rat mammary tumors induced by N-methyl-N-nitrosurea (NMU) and normal mammary gland
Rat mammary tumors induced by N-methyl-N-nitrosurea (NMU) and normal mammary gland
ORGANISM(S): Rattus norvegicus 
2007-09-22 | E-GEOD-1872 | biostudies-arrayexpress
MetabolomicsUntargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models
The application of ketogenic diet (KD) (high fat/low carbohydrate/adequate protein) as an auxiliary cancer therapy is a field of growing attention. KD provides sufficient energy supply for healthy cells, while possibly impairing energy production in highly glycolytic tumor cells. Moreover, KD regula...
2019-10-08 | MTBLS1066 | MetaboLights
TranscriptomicsThe Snf1-Related Kinase, Hunk, Is Essential for Mammary Tumor Metastasis
We previously identified a novel SNF1/AMPK-related protein kinase, Hunk, from a mammary tumor arising in an MMTV-neu transgenic mouse. The function of this kinase is unknown. Using targeted deletion in mice, we now demonstrate that Hunk is required for the metastasis of c-myc-induced mammary tumors,...
ORGANISM(S): Mus musculus 
2009-12-31 | E-GEOD-14226 | biostudies-arrayexpress
ProteomicsProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - primary mammary fibroblasts treated with IL1-beta
Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079966 | MassIVE
MetabolomicsArginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
Defective arginine synthesis, due to the silencing of argininosuccinate synthase 1 (ASS1), is a common metabolic vulnerability in cancer, known as arginine auxotrophy. Understanding how arginine depletion kills arginine-auxotrophic cancer cells will facilitate the development of anti-cancer therapeu...
2019-11-07 | MTBLS745 | MetaboLights
ProteomicsProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - primary mammary fibroblasts treated with TGF-beta
Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079968 | MassIVE
ProteomicsProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - primary mammary fibroblasts
Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079940 | MassIVE
MetabolomicsDynamic single-cell metabolomics reveals cell-cell interaction between tumor cells and macrophages

Single-cell metabolomics reveals cell heterogeneity and elucidates intracellular molecular mechanisms. However, general concentration measurement of metabolites can only provide a static delineation of metabolomics, lacking the metabolic activity information of biological pathways. Herein, we dev...

2025-04-14 | MTBLS11091 | MetaboLights
ProteomicsProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - tumor-distant tissue sections
Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079950 | MassIVE
Sort   by:  
 Page size