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TranscriptomicsA compendium of hematopoietic regulators, chromatin modifiers and basal transcription factors occupy CBF-MYH11/RUNX1 target genes
Different mechanisms for CBF-MYH11 function in acute myeloid Leukemia (AML) with inv(16) have been proposed such as tethering of RUNX1 outside the nucleus, interference with transcription factor complex assembly and recruitment of histone deacetylases, all resulting in transcriptional repression of ...
ORGANISM(S): Homo sapiens 
2013-09-09 | E-GEOD-46044 | biostudies-arrayexpress
UnknownGenome-wide binding of transcription factors in inv(16) acute myeloid leukemia.
Not available
S-EPMC4535528 | biostudies-literature
UnknownEfficient 1400-1600 nm Circularly Polarized Luminescence from a Tuned Chiral Erbium Complex.
Not available
S-EPMC9545264 | biostudies-literature
GenomicsOncofusion protein AML1-ETO targets ERG factor binding sites in AML
ERG has been identified as an essential factor for the function and maintenance of adult hematopoietic stem cells and high ERG expression is a negative prognostic marker for treatment outcome in AML. The molecular function of ERG and its interplay with other factors is however largely unknown. Here ...
ORGANISM(S): Homo sapiens 
2012-09-18 | E-GEOD-23730 | biostudies-arrayexpress
UnknownTwo and Three-Dimensional Echocardiography in Primary Mitral Regurgitation: Practical Hints to Optimize the Surgical Planning.
Not available
S-EPMC8295501 | biostudies-literature
UnknownGiant Left Main Coronary Artery Aneurysm: A Decade-Long Evolution of an Incidental Finding.
Not available
S-EPMC11911917 | biostudies-literature
UnknownAML associated oncofusion proteins PML-RARA, AML1-ETO and CBFB-MYH11 target RUNX/ETS-factor binding sites to modulate H3ac levels and drive leukemogenesis.
Not available
S-EPMC5355061 | biostudies-literature
UnknownMLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia.
Not available
S-EPMC5474565 | biostudies-literature
UnknownDeformation Imaging by Strain in Chronic Heart Failure Over Sacubitril-Valsartan: A Multicenter Echocardiographic Registry.
Not available
S-EPMC10053272 | biostudies-literature
UnknownAdvances in mosquito repellents: effectiveness of citronellal derivatives in laboratory and field trials.
Not available
S-EPMC9826021 | biostudies-literature
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