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TranscriptomicsNi2+-dependent and PsaR-mediated regulation of the virulence genes pcpA, psaBCA, and prtA in Streptococcus pneumoniae
Previous studies have shown that the transcriptional regulator PsaR regulates the expression of the PsaR regulon consisting of genes encoding choline binding protein (PcpA), the extracellular serine protease (PrtA), and the Mn2+-uptake system (PsaBCA), in the presence of manganese (Mn2+), zinc (Zn2+...
ORGANISM(S): Streptococcus pneumoniae D39 
2015-11-20 | E-GEOD-73818 | biostudies-arrayexpress
TranscriptomicsD39 wild-type vs D39 ΔadcR In CDM with 0.3 mM Ni2+
By using the transcriptomic approach, we have elucidated the effect of Ni2+ on the global gene expression of S. pneumoniae D39 by identifying several differentially expressed genes/operons in the presence of a high extracellular concentration of Ni2+. The genes belonging to the AdcR regulon (adcRCBA...
ORGANISM(S): Streptococcus pneumoniae D39 
2015-11-20 | E-GEOD-73851 | biostudies-arrayexpress
TranscriptomicsHigh Ni2+ vs Low Ni2+
By using the transcriptomic approach, we have elucidated the effect of Ni2+ on the global gene expression of S. pneumoniae D39 by identifying several differentially expressed genes/operons in the presence of a high extracellular concentration of Ni2+. The genes belonging to the AdcR regulon (adcRCBA...
ORGANISM(S): Streptococcus pneumoniae D39 
2015-11-20 | E-GEOD-73850 | biostudies-arrayexpress
TranscriptomicsFucose-mediated transcriptional activation of the fcs operon by FcsR in Streptococcus pneumoniae
In this study, we explore the impact of fucose on the transcriptome of S. pneumoniae D39. The expression of various genes and operons, including the fucose uptake PTS and utilization operon (fcs operon), was altered in the presence of fucose. By means of quantitative RT-PCR and β-galactosidase analy...
ORGANISM(S): Streptococcus pneumoniae D39 
2015-04-23 | E-GEOD-65673 | biostudies-arrayexpress
TranscriptomicsComparison of the Streptococcus pneumoniae D39 malR Mutant compared to D39 wild-type
The maltose regulon (mal regulon) has previously been shown to consist of the mal gene cluster (malQP, malXCD and malAR operons) in Streptococcus pneumoniae. In this study, we have further elucidated the complete mal regulon in S. pneumoniae D39 using microarray analyses and β-galactosidase assays. ...
ORGANISM(S): Streptococcus pneumoniae D39 
2015-04-23 | E-GEOD-65548 | biostudies-arrayexpress
TranscriptomicsComparison of the Streptococcus pneumoniae D39 ccpA Mutant compared to D39 wild-type
The maltose regulon (mal regulon) has previously been shown to consist of the mal gene cluster (malQP, malXCD and malAR operons) in Streptococcus pneumoniae. In this study, we have further elucidated the complete mal regulon in S. pneumoniae D39 using microarray analyses and β-galactosidase assays. ...
ORGANISM(S): Streptococcus pneumoniae D39 
2015-04-23 | E-GEOD-65547 | biostudies-arrayexpress
TranscriptomicsMaltose vs Glucose
The maltose regulon (mal regulon) has previously been shown to consist of the mal gene cluster (malQP, malXCD and malAR operons) in Streptococcus pneumoniae. In this study, we have further elucidated the complete mal regulon in S. pneumoniae D39 using microarray analyses and β-galactosidase assays. ...
ORGANISM(S): Streptococcus pneumoniae D39 
2015-04-23 | E-GEOD-65549 | biostudies-arrayexpress
UnknownGlobal anaesthesia practice using inguinal hernia surgery as a tracer condition: a secondary analysis of an international prospective cohort study.
Not available
S-EPMC12519944 | biostudies-literature
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