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TranscriptomicsMapping the Regulatory Network for Salmonella Typhimurium Invasion
Using RNAseq, the goal of the study is to investigate transcription factor regulation of virulence genes in 14028s Salmonella Typhimurium grown in SPI-1-inducing conditions. Transcription factors were cloned into pBAD24. RNA levels were compared in 14028s Salmonella Typhimurium with the transcriptio...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2015-08-17 | E-MTAB-3765 | biostudies-arrayexpress
TranscriptomicsDifferential stress transcriptome landscape of historic and recently emerged hypervirulent strains of Clostridium difficile strains determined using RNA-seq
Purpose: To determine how divergent strains of C. difficile respond to environmental changes, the transcriptomes of two historic and two recently isolated hypervirulent strains were analyzed following nutrient shift and osmotic shock. Methods: Following nutrient shift and osmotic shock, mRNA profil...
ORGANISM(S): [Clostridium] difficile 
2013-11-06 | E-GEOD-50497 | biostudies-arrayexpress
ProteomicsIdentification of Putative Early Atherosclerosis Biomarkers by Unsupervised Deconvolution of Heterogeneous Vascular Proteomes
Coronary artery disease remains a leading cause of death in industrialized nations, and early detection of disease is a critical intervention target in order to effectively treat patients and manage risk. Proteomic analysis of mixed tissue homogenates may obscure subtle protein changes that occur un...
ORGANISM(S): Homo Sapiens 
2021-01-21 | PXD016730 | panorama
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