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ProteomicsBlood-based Diagnostics of Pediatric Tuberculosis: A Prospective Case-controlled Study
Background Pediatric tuberculosis (TB) diagnosis is often challenging due to difficultly obtaining diagnostic respiratory specimens, which may contain low concentrations of Mycobacterium tuberculosis (Mtb) bacilli. However, we have reported that an immuno-affinity liquid chromatography-tandem mass s...
ORGANISM(S): Homo Sapiens 
PXD053274 | panorama
TranscriptomicsHigh-resolution genome-wide copy-number analysis suggests a monoclonal origin of multi-focal prostate cancer
Many human cancers present as multi-focal lesions. Understanding the clonal origin of multi-focal cancers is of both etiological and clinical importance. The molecular basis of multi-focal prostate cancer has previously been explored using only a limited number of isolated markers and, although inde...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-29569 | biostudies-arrayexpress
TranscriptomicsIdentification of ZDHHC14 as a novel tumor suppressor gene commonly downregulated in human cancers
Genomic changes affecting tumor suppressor genes (TSGs) are fundamental to cancer. We applied SNP array analysis on a panel of testicular germ cell tumors (TGCTs) to search for novel TSGs and identified a frequent small deletion on 6q25.3 containing just one gene; ZDHHC14. The expression of ZDHHC14,...
ORGANISM(S): Homo sapiens 
2012-12-31 | E-GEOD-35216 | biostudies-arrayexpress
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