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GenomicsTranscriptome analysis of Mapt-EGFP+ and Mapt-EGFP- myenteric cells
Transcriptome analysis of Mapt-EGFP+ and Mapt-EGFP- myenteric cells
PRJNA822404 | ENA
ProteomicsDistinct cell type-specific protein signatures in GRN and MAPT genetic subtypes of frontotemporal dementia
INTRODUCTION: Frontotemporal dementia (FTD) is characterized by progressive atrophy of frontal and/or temporal cortices and considerable clinical, pathological, and genetic heterogeneity. METHODS: Frontal and temporal cortex tissues from FTD-GRN (n=9), FTD-MAPT (n=13), and non-demented controls (n=1...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD031419 | Pride
Frontotemporal dementia  grn  mapt  human brain proteomics  cell type enrichment 
GenomicsNovel G342L MAPT mutation in familial Progressive Supranuclear Palsy Syndrome
Novel G342L MAPT mutation in familial Progressive Supranuclear Palsy Syndrome
PRJEB73767 | ENA
TranscriptomicsTranscriptome analysis of Mapt-EGFP+ and Mapt-EGFP- myenteric cells
Mapttm1(EGFP)Klt/J mice (Mapt-EGFP; The Jackson Laboratory, Bar Harbor, ME, USA; stock 004779) carry a knock-in of the EGFP coding sequence in the first exon of the microtubule-associated protein tau (Mapt) gene producing a cytoplasmic EGFP fused to the first 31 amino acids of MAPT. EGFP expression ...
ORGANISM(S): Mus musculus 
2024-02-14 | GSE199990 | GEO
TranscriptomicsCancer-specific association between Tau (MAPT) and cellular pathways, clinical outcome, and drug response
Tau (MAPT) is a microtubule-associated protein causing frequent neurodegenerative diseases or inherited frontotemporal lobar degenerations. Emerging evidence for non-canonical functions of Tau in DNA protection and P53 regulation suggests its involvement in cancer. Indeed, Tau expression correlates ...
ORGANISM(S): Homo sapiens 
2022-11-27 | E-MTAB-8166 | biostudies-arrayexpress
GenomicsDevelopment of MAPT S305 mutation models exhibiting elevated 4R tau expression, resulting in altered neuronal and astrocytic function [Targeted MAPT ISO-seq]
Development of MAPT S305 mutation models exhibiting elevated 4R tau expression, resulting in altered neuronal and astrocytic function [Targeted MAPT ISO-seq]
PRJNA1171850 | ENA
GenomicsRiboseq and Quantseq of neuroblastoma cell line SH-SY5Y expressing MAPT-AS1 constructs
Riboseq and Quantseq of neuroblastoma cell line SH-SY5Y expressing MAPT-AS1 constructs
PRJEB42048 | ENA
GenomicsMAPT-derived circTau6 induces tau pathogenesis and neurodegeneration by encoding Tau variants
MAPT-derived circTau6 induces tau pathogenesis and neurodegeneration by encoding Tau variants
PRJNA1458083 | ENA
TranscriptomicsRiboseq and Quantseq of neuroblastoma cell line SH-SY5Y expressing MAPT-AS1 constructs
The aim of this experiment was to assess the on- and off-target effects of MAPT-AS1 expression, and whether mutations/deletions to MAPT-AS1 alter these effects. SHSY5Y cells stably expressing variants of MAPT-AS1 were analyzed by Riboseq and Quantseq.
ORGANISM(S): Homo sapiens 
2021-03-20 | E-MTAB-9921 | biostudies-arrayexpress
GenomicsBulk RNA sequencing of mutant MAPT over-expression in neural organoids
Bulk RNA sequencing of mutant MAPT over-expression in neural organoids
PRJEB106124 | ENA
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