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TranscriptomicsGene expression changes with induction of in-vitro platinum-resistance in ovarian cancer cell lines.
We treated 8 human ovarian cancer cell lines with cisplatin in treatment/recovery cycles to induce in-vitro resistance to the drug. Microarrays measured gene expression at baseline and after each dose schedule (after recovery). OVCA cells lines (T8, OVCAR5, OV2008, IGROV1, C13, A2780S, A2780CP, and ...
ORGANISM(S): Homo sapiens 
2011-10-02 | E-GEOD-23553 | biostudies-arrayexpress
TranscriptomicsOvarian Cancer Dataset
Background. Genome-wide expression changes are associated with development of chemoresistance in patients with ovarian cancer (OVCA); the BCL2 antagonist of cell death (BAD) apoptosis pathway may play a role in clinical outcome. Methods. We analyzed specimens and/or genomic data from 1,406 patients...
ORGANISM(S): Homo sapiens 
2011-10-02 | E-GEOD-23554 | biostudies-arrayexpress
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