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TranscriptomicsGene expression changes with induction of in-vitro platinum-resistance in ovarian cancer cell lines.
We treated 8 human ovarian cancer cell lines with cisplatin in treatment/recovery cycles to induce in-vitro resistance to the drug. Microarrays measured gene expression at baseline and after each dose schedule (after recovery). OVCA cells lines (T8, OVCAR5, OV2008, IGROV1, C13, A2780S, A2780CP, and ...
ORGANISM(S): Homo sapiens 
2011-10-02 | E-GEOD-23553 | biostudies-arrayexpress
TranscriptomicsOvarian Cancer Dataset
Background. Genome-wide expression changes are associated with development of chemoresistance in patients with ovarian cancer (OVCA); the BCL2 antagonist of cell death (BAD) apoptosis pathway may play a role in clinical outcome. Methods. We analyzed specimens and/or genomic data from 1,406 patients...
ORGANISM(S): Homo sapiens 
2011-10-02 | E-GEOD-23554 | biostudies-arrayexpress
TranscriptomicsOvarian cancer cell lines [Baseline profiling]
Analysis of a panel of 41 human ovarian cancer cell lines for the study of ovarian cancer biology, drug response and drug sensitivity. Ovarian cancer cell lines were either obtained from the American Type Culture Collection (ATCC, Manassas, VA) (CAOV3, OV90, OVCAR3, SKOV3, TOV112D), the European Col...
ORGANISM(S): Homo sapiens 
2012-06-30 | E-GEOD-34615 | biostudies-arrayexpress
TranscriptomicsPathways of ovarian cancer development
In order to evaluate pathways that drive the development of ovarian cancer, we compared Affymetrix expression profiles from normal ovarian surface epithelium to those from primary ovarian carcinomas. mRNA expression profiles for 57 ovarian carcinomas and 12 ovarian normal samples.
ORGANISM(S): Homo sapiens 
2015-06-22 | E-GEOD-66957 | biostudies-arrayexpress
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