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GenomicsImpact of MAREMO peptide MP5 on gene expression in tumor cells
Impact of MAREMO peptide MP5 on gene expression in tumor cells
PRJEB79908 | ENA
TranscriptomicsTargeting the MAtrix REgulating MOtif, MAREMO, abolishes hallmarks of cancer
Tumor targeted therapies have been largely inefficient due to lack of concomitant effects on the tumor microenvironment (TME). We investigated the MAtrix REgulating MOtif (MAREMO) mimicking peptide MP5, that inhibits the pro-tumorigenic extracellular matrix (ECM) molecule tenascin-C, using immunocom...
ORGANISM(S): Mus musculus 
2024-01-20 | E-MTAB-13677 | biostudies-arrayexpress
TranscriptomicsImpact of MAREMO peptide MP5 on gene expression in tumor cells
After seeding and growth for 18 hours in 10%FBS/DMEM, NT193M cells were incubated with MP5 (50 microgr/ml) in 0.1% FCS/DMEM for 72 hours before collection of RNA and RNA seq analysis. Expression and p-values of the genes differentially expressed in MP5 (compared to PBS) treated NT193M cells with p-...
ORGANISM(S): Mus musculus 
2024-09-25 | E-MTAB-14437 | biostudies-arrayexpress
GenomicsTargeting the MAtrix REgulating MOtif, MAREMO, abolishes hallmarks of cancer
Targeting the MAtrix REgulating MOtif, MAREMO, abolishes hallmarks of cancer
PRJEB71628 | ENA
ProteomicsTenascin-C shapes TRAIL control over tumor immunity
TRAIL cytotoxicity is exploited as anti-cancer therapy since many years, however incomplete knowledge is generating many obstacles. Here, we address whether the highly abundant extracellular matrix molecule tenascin-C (TNC) orchestrating an immune suppressive tumor microenvironment and binding TRAIL...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-15 | PXD045388 | Pride
Shotgun proteomics Tenascin c Trail Maremo peptide mp5 
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