Sort   by:  
 Page size 
TranscriptomicsRole of miR-125b in B-cell acute lymphoblastic leukemia (B-ALL)
B-cell acute lymphoblastic leukemia (B-ALL) is often associated with chromosomal translocations leading to the deregulation of proto-oncogenes. MicroRNAs can also be affected by chromosomal alterations and thus contribute to carcinogenesis. The microRNA miR-125b-1 is over-expressed in B-ALL cases wi...
ORGANISM(S): Mus musculus 
2012-06-20 | E-GEOD-30647 | biostudies-arrayexpress
MetabolomicsPeripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models
Reversible and sub-lethal stresses to the mitochondria elicit a program of compensatory responses that ultimately improve mitochondrial function, a conserved anti-aging mechanism termed mitohormesis. Here, we show that harmol, a member of the beta-carbolines family with anti-depressant properties, i...
2023-05-26 | MTBLS7533 | MetaboLights
TranscriptomicsSpt6 Levels are Modulated by PAAF1 and 26S Proteasome to Regulate the HIV-1 LTR and a Subset of Cellular Genes involved in Cancer.
Effect of PAAF1 and Spt6 knock-down on gene expression. Total RNAs were extracted from HeLa-LTR-Luc cells in which PAAF1 or Spt6 had been knock down by a specific siRNA or HeLa-LTR-Luc cells that had been transfected with a control siRNA (“si Neg”). Differentially expressed genes in PAAF1 knock-down...
ORGANISM(S): Homo sapiens 
2012-05-28 | E-GEOD-32033 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Bordetella pertussis strains in response to glutamate availablility
B. pertussis mid-log phase cultures were washed twice and resuspended at a starting OD at 600 nm of 0.05 in media containing various concentrations of glutamate.
ORGANISM(S): Bordetella parapertussis 
2006-12-04 | E-TABM-99 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Bordetella pertussis from mid-log phase cultures diluted to two concentrations and grown beyond the log to stationary phase transition to determine growth phase-associated patterns of transcript abundance
B. pertussis mid-log phase cultures were diluted in modified Stainer-Scholte medium to a starting optical density at 600 nm of 0.03 to 0.05, then grown at 37 C with shaking until three hours beyond the log to stationary phase transition.
ORGANISM(S): Bordetella parapertussis 
2006-12-31 | E-TABM-100 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Bordetella pertussis from mid-log phase cultures diluted to two concentrations and sampled at multiple points along the growth curve to determine growth phase-associated patterns of transcript abundance
B. pertussis mid-log phase cultures were diluted in modified Stainer-Scholte medium to a starting optical density at 600 nm of 0.03 to 0.05, then grown at 37 C with shaking until stationary phase. Samples were taken at multiple points along the growth curve.
ORGANISM(S): Bordetella pertussis 
2006-12-31 | E-TABM-101 | biostudies-arrayexpress
TranscriptomicsThe 3’UTR of FMR1 mRNA is a target of miR101, miR129-5p and miR-221: implications for the molecular pathology of FXTAS at the synapse.
While FMR1 is silenced in Fragile X syndrome (FXS), its expression is elevated (2-8 fold) in premutated individuals. These people may develop the Fragile X-associated Tremor Ataxia Syndrome (FXTAS), a late onset neurodegenerative disorder characterized by ataxia and parkinsonism. In addition, people...
ORGANISM(S): Mus musculus 
2013-03-07 | E-GEOD-43670 | biostudies-arrayexpress
UnknownKIR3DL1/HLA-B Subtypes Govern Acute Myelogenous Leukemia Relapse After Hematopoietic Cell Transplantation.
Not available
S-EPMC5501362 | biostudies-literature
UnknownCathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential.
Not available
S-EPMC2670444 | biostudies-literature
UnknownConstruction of Unusual Indole-Based Heterocycles from Tetrahydro-1H-pyridazino[3,4-b]indoles.
Not available
S-EPMC7571100 | biostudies-literature
Sort   by:  
 Page size